doxycycline


Also found in: Dictionary, Thesaurus, Legal, Wikipedia.

doxycycline

 [dok″sĕ-si´klēn]
a broad-spectrum semisynthetic antibiotic, used as the hyclate and calcium salts against a wide range of gram-positive and gram-negative organisms; administered orally or intravenously.

dox·y·cy·cline

(doks'ē-sī'klēn),
A broad-spectrum antibiotic.

doxycycline

/doxy·cy·cline/ (dok″se-si´klēn) a semisynthetic broad-spectrum tetracycline antibiotic, active against a wide range of gram-positive and gram-negative organisms; used also as d. calcium and d. hyclate.

doxycycline

(dŏk′sĭ-sī′klēn′, -klĭn)
n.
A broad-spectrum antibiotic, C22H24N2O8, derived from tetracycline.

doxycycline

[dok′sisī′klēn]
a tetracycline antibiotic.
indications It is prescribed in the treatment of infections caused by susceptible bacterial strains, especially Chlamydia, Rickettsia, and Mycoplasma.
contraindications Renal or liver dysfunction or known hypersensitivity to this drug or to other tetracycline medication prohibits its use. It is not given during pregnancy or to children less than 8 years of age.
adverse effects Among the more serious adverse reactions are GI disturbances, phototoxicity, potentially serious superinfections, and hypersensitivity reactions. Discoloration of teeth may occur in children exposed to the drug in utero or under 8 years of age.

doxycycline

Infectious disease A broad-spectrum antibiotic used for rickettsiosis–eg, Rocky mountain spotted fever, typhus fever, Q fever, rickettsialpox, tick fevers, RTIs from Mycoplasma pneumoniae, lymphogranuloma venereum, trachoma, inclusion conjunctivitis, etc, due to Chlamydia trachomatis, psittacosis–C psittaci, nongonococcal urethritis–Ureaplasma urealyticum, relapsing fever–Borrelia recurrentis, gram-negative microorganisms: Chancroid–Haemophilus ducreyi, plague–Yersinia pestis, tularemia–Francisella tularensis, cholera–Vibrio cholerae, Campylobacter fetus, Brucella spp, Bartonella bacilliformis, Calymmatobacterium granulomatis, malaria prophylaxis–Plasmodium falciparum in travelers to chloroquine and/or pyrimethamine-sulfadoxine resistant areas Adverse effects GI tract disturbances, anorexia, N&V, diarrhea, glossitis, dysphagia, enterocolitis, anogenital Candida overgrowth, photophobia

dox·y·cy·cline

(doks'ē-sī'klēn)
A broad-spectrum antibiotic.

doxycycline

A tetracycline antibiotic drug, deoxytetracycline, that is well absorbed when taken by mouth, even after food. Doxycycline is also used for the prophylaxis of MALARIA. The drug is on the WHO official list. Brand names are Periostat and Vibramycin.

dox·y·cy·cline

(doks'ē-sī'klēn)
A broad-spectrum antibiotic.

doxycycline

a second-generation, lipid-soluble tetracycline derivative with greater activity against anaerobes and intracellular bacteria, and a longer half-life. Used as the monohydrate.
References in periodicals archive ?
Doxycycline susceptibilities ranged from 47% for A.
Nor were there significant differences among men with chlamydia infections, with a clinical cure rate of 87% for azithromycin and 78% for doxycycline.
Young heartworms are killed more quickly by the combination of ivermectin and doxycycline, so if the infection was caught early, later treatment with Immiticide is less likely to be needed.
Doxycycline does work for the outpatient management of PID, just not quite as well as azithromycin, so it seems to us like a perfectly good choice when personal circumstances dictate.
On day 1, mean doxycycline content for the three compounded tablet formulations was 89%, 98%, and 116% (3/5, 5/5, and 1/5 samples within acceptable ranges); day 21 content range was 86% to 112% (1/5, 5/5, and 4/5 samples within acceptable ranges).
We knew from the beginning that doxycycline would not be as effective as prednisolone.
While the fear response was 60 percent lower in those who had doxycycline in the first session, the researchers found that, importantly, other cognitive measures -- including sensory memory and attention -- were not affected.
Treatment efficacy for doxycycline, as determined by microbial cure, was calculated by using the number of treated men with a negative repeat test result by NAAT as the numerator and the number of treated men who underwent repeat testing as the denominator.
At the 31st day, the seven other groups received one of the following treatment regimens: doxycycline (oral, 40 mg/kg every 12 h for 14 days); ciprofloxacin, ofloxacin or levofloxacin (oral, 40 mg/kg/day of body weight for 14 days); and one of doxycycline-ciproflox-acin, doxycycline-ofloxacin or doxycycline-levofloxacin combinations at the same doses mentioned above (i.
The DoJ's antitrust division sent subpoenas last year to two generic drugmakers -- Endo International Plc and Mylan -- seeking information on their doxycycline products.
3) Therapeutic failure and relapse develop in 8% and 16%, respectively, of patients with acute brucellosis receiving doxycycline plus rifampin for 45 days compared to 2% and 5.
3,4] Doxycycline is a best choice of initial antimicrobial treatment for scrub typhus.