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John Langdon H., English physician, 1828-1896. See: Down syndrome.


1. Fine, soft, fluffy feathers forming the first plumage of a young bird and underlying the contour feathers in certain adult birds.
2. A soft, silky, or feathery substance, such as the first growth of a human beard.


Etymology: AS, adune, off hill
(of a computer) not operating as a result of malfunction or maintenance or for other reasons.


the soft, small feathers lacking BARBULES that cover the body of a bird and aid heat retention.

Patient discussion about down

Q. Can Down syndrome occur again? A few years ago, at the age of 32 my sister gave birth to a child that was diagnosed with Down syndrome. Now, at the age of 37 she's pregnant again. Can she have another baby with Down? Does the fact she has a baby with Down means she has higher risk for a second baby with Down?

A. - Older women especially after 35 years
- Previuosly child with Down Syndrome

Video link


Q. assessment of down syndrom

A. down syndrome is a very easy diagnosis - it just need a chromosome check and seeing 3 (instead 2) chromosomes number 21. -

Q. what does enlarged heart mean? is it linked to down syndrome? My wife is 16 weeks pregnant. we did a prenatal US and we were told that the baby hes an enlarged heart and that we are advised to do amniocentesis. A friend of mine had a baby with down syndrome, and he was toled that if they have done this procedure, the doctors could have find it on time and abort the pregnancy. Is there a clear connection between the enlarged hart and the fact that the doctor advised us to do this procedure to down syndrome?

A. Down syndrome is associated with several kinds of heart problems. those problems can cause an enlarged heart but usually it will appears as a post-natal complication.
The protocol that most obstetrics use is that if there is anything abnormal in the US there is an automatic referral to an amniocentesis procedure.
the US has a lot of false alarms, so they must check with the more accurate procedure.

More discussions about down
References in periodicals archive ?
Buyers will often expect a downstairs bathroom in a particular area or type of property, so moving the bathroom upstairs could be a waste of time and money.
Julie said: "A band was practising upstairs, and just as one of them walked through the door to go downstairs, the lights all went out.
The downstairs doublebedroom annexe has its own en suite, separate kitchen and living area and there is a further large lounge and WC.
It can't be sensible to send the public through the pool area or upstairs into the gym for a toilet, when there are perfectly good toilets that have always been available (and still are) downstairs for years.
By day Upstairs Downstairs is a classy restaurant, but for the Club Monte Cristo night, it will be transformed into Parisian chic venue.
A spokesman for Yale said: "The prospect of creeping downstairs in the darkness can be daunting, and something couples will avoid.
WHERE: Patrick Road, Yardley WHAT: Extended traditional semi with entrance hall, downstairs toilet, lounge, dining room, sun lounge, enlarged fitted kitchen, downstairs toilet, family shower room, four bedrooms, central heating, double glazing, multi car off road parking, garage, back garden with decked areas and raised fish pond.
UPSTAIRS Downstairs has been axed by BBC bosses after admitting defeat to rival channel ITV's hit show Downton Abbey.
As feisty parlour maid Rose Buck, actress Jean Marsh was one of the biggest stars of iconic 1970s series Upstairs Downstairs, as well as the brains behind it.
MILLIONS of viewers will tune in for the return of Upstairs Downstairs tonight - and they may not believe their eyes.
And they will soon discover how handy it is to have a downstairs loo.