Such a combined endo-perio lesion, or apicomarginal defect, carries the risk of epithelial downgrowth
along the denuded root surface following apical surgery (2).
This analysis demonstrated good evidence of epithelialization along the skin-implant interface with minimal downgrowth
In endodontic-periodontal lesions, the cause of the lesion is endodontic or periodontal in origin, and the patient may benefit from undergoing root canal therapy first [20, 21] because pulpal infection could promote marginal epithelial downgrowth
along the root surfaces of the teeth .
reported a graft rejection rate of 3.5%, with no cases of infection or epithelial downgrowth
In the present study, the 1-wall intrabony defects in the OFD group exhibited a large ratio of JE downgrowth
on root surface as compared to their counterparts in the OFD group, which suggests that the number of bone walls might have inherently compromised wound stability due to the defect morphology.
 (2015) Hyperparakeratotic stratified squamous cyst lining epithelium and downgrowth
of broad and bulbous epithelial ridges with pushing-border invasion into the fibrous Kamarthi et al.
of rete ridges, small junctional nests, heavily pigmented epidermis, and melanophages.
The removal of the outer epithelium is perhaps acting similarly to a periodontal membrane, delaying the downgrowth
of epithelial cells and allowing more time for a connective tissue attachment to form, which takes five times longer .
This continuous mechanical disruption prevented epithelial downgrowth
and formation of a stable inner lining.
is an uncommon but serious complication which is characterized by cysts or translucent membranes (derived from ocular surface epithelial cells) covering the intraocular structures like corneal endothelium, iris surface, and ciliary body.
Secondary cysts: It is caused by epithelial downgrowth
following trauma /surgery/drugs, eg.
On a superficial biopsy, the hyperplastic downgrowth
of the epidermis and the cords of basaloid tumor cells give a pseudoinfiltrative appearance mimicking the features of SCC.