Doubly heterozygous | definition of doubly heterozygous by Medical dictionary
in the analysis of linkage between two loci, denoting that genotype in which a parent is heterozygous at both loci, the state that on average contains the maximum information about the linkage.
dou·bly het·er·o·zy·gous (dŭb'lē het'ĕr-ō-zī'gŭs)
Denoting that genotype in which a parent is heterozygous at both loci, the state that on average contains the maximum information about the linkage.
References in periodicals archive
We describe the case of doubly heterozygous
Hb-SD Punjab in a 8 year old girl who presented with ischaemic stroke.
Homozygous sickle cell anaemia (Hb SS) is the most common while sickle cell trait, doubly heterozygous
conditions of Hb SC and Hb Sssthal also cause sickling disease2.
It would then appear that 1 of our 2 patients who is homozygous for the FVL mutation and heterozygous for the prothrombin G20210A mutation has a substantially greater risk compared with a doubly heterozygous
patient, possibly explaining in part the fact that this patient had 10 episodes of thrombosis by the time of analysis.