doubly heterozygous

dou·bly het·er·o·zy·gous

in the analysis of linkage between two loci, denoting that genotype in which a parent is heterozygous at both loci, the state that on average contains the maximum information about the linkage.

dou·bly het·er·o·zy·gous

(dŭb'lē het'ĕr-ō-zī'gŭs)

Denoting that genotype in which a parent is heterozygous at both loci, the state that on average contains the maximum information about the linkage.

References in periodicals archive ?

We describe the case of doubly heterozygous Hb-SD Punjab in a 8 year old girl who presented with ischaemic stroke.

Haemoglobin sickle D disease: A presentation with ischaemic stroke

Homozygous sickle cell anaemia (Hb SS) is the most common while sickle cell trait, doubly heterozygous conditions of Hb SC and Hb Sssthal also cause sickling disease2.

SUDDEN DEATH OF YOUNG RECRUIT WITH UNDIAGNOSED SICKLE CELL DISORDER

It would then appear that 1 of our 2 patients who is homozygous for the FVL mutation and heterozygous for the prothrombin G20210A mutation has a substantially greater risk compared with a doubly heterozygous patient, possibly explaining in part the fact that this patient had 10 episodes of thrombosis by the time of analysis.

Combined Factor V Leiden and Prothrombin Genotyping in Patients Presenting With Thromboembolic Episodes