double dummy

double dummy

A technique for retaining the blinding of a clinical trial, where the two treatments cannot be made identical. Supplies are prepared for Treatment A (active and indistinguishable placebo) and for Treatment B (active and indistinguishable placebo); subjects then take two sets of treatment, either A (active) and B (placebo), or A (placebo) and B (active).
References in periodicals archive ?
The Yoda report will become an essential part of our communication dossier with the [US Food & Drug Administration] and [European Medicines Agency] when we justify our clinical double dummy design for the concomitant use of steroids for the next Traumakine studies."
AMPLIFY was a 24-week treatment, multi-centre, randomised, double-blind, double dummy, parallel-group trial that aimed to assess the safety and efficacy of aclidinium bromide/formoterol twice-daily compared to its component parts given individually twice a day and once-daily tiotropium.
Ramsey's double dummy opened up space, before he tucked a rightfooted shot into the net.
Newport then put together a move with a double dummy run in midfield and Kevin Morgan got in.
An injury to Charvis after 57 disrupted the Falcons to the extent they conceded a try 60 seconds later when Newport ran a double dummy in midfield and Kevin Morgan raced in.
Lee's double dummy left Barrow and Hughes flat-footed and he crossed the line in the corner.
In the 1987 British Grand Prix Mansell pulled off a sensational double dummy at 200mph to beat Piquet.
Results from the double-blind, double dummy, event driven trial are expected in 2018.
The Phase III study was conducted in Japan as a double-blind, double dummy controlled study between rotigotine transdermal patch, ropinirole oral tablets and placebo.
Topical steroids versus systemic antifungals in the treatment of chronic paronychia: an open, randomized double-blind and double dummy study.
SAILING (ING111762) is an ongoing Phase III, multicentre, double blind, double dummy study to compare the efficacy and safety of dolutegravir 50mg once-daily to raltegravir 400mg twice-daily in treatment-experienced, integrase inhibitor-naive adults with HIV-1.
The Phase III, 12-week, randomised, multicentre, double-blind, double dummy, active-controlled studies involved more than 450 gouty arthritis patients for whom the standard anti-inflammatory therapies, non-steroidal anti-inflammatory drugs (NSAIDs) or colchicine, were inadequate or inappropriate.