double bubble sign

dou·ble bub·ble sign

in pediatric radiology, appearance of the dilated air-filled stomach and duodenal bulb, associated with duodenal atresia or web, less often midgut volvulus.
Farlex Partner Medical Dictionary © Farlex 2012
A radiologic finding in which there are 2 distinct gas pockets in an upper GI radiocontrast study, seen in those with atresia of the 2nd segment of the duodenum, 20–30% of whom have Down syndrome; the larger left bubble corresponds to gastric gas; the smaller right bubble corresponds to gas in the duodenal bulb. The double bubble sign may also occur in an annular pancreas with/without duodenal atresia, duodenal stenosis, peritoneal bands and volvulus. The sign is correspondingly smaller if there is passage of air
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
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The double bubble sign indicates the presence of duodenal obstruction that can be caused by a number of intrinsic or extrinsic etiologies.
Duodenal atresia is the causative entity most commonly linked with a double bubble sign. Duodenal atresia is found in 1 in 10,000 newborns and is typically associated with other congenital anomalies; 30% of children with duodenal atresia have Down's syndrome.