dot positivity

A rarely used term of art referring to minimal positive staining of a particular antigen (in dots, hence the name) due to aggregation of staining material in the Golgi apparatus by immunohistochemistry, which serves to establish the cell’s lineage—e.g., T cells, Ewing sarcoma cells, fibrosarcoma, neuroblastoma, etc.

References in periodicals archive ?

Cytochemically, these cells were negative for myeloperoxidase, Sudan black, acid phosphatase and periodic acid Schiff, while few cells showed granular and dot positivity with non-specific esterase as described in an older literature [5].

De-novo CD5 + B- prolymphocytic leukemia (PLL) presenting at younger age with favourable outcome/Kucuk yasta olumlu prognoz ile seyreden de-novo CD5 + B- prolenfositik losemi (PLL)

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