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dose

 [dōs]
the quantity to be administered at one time, as a specified amount of medication or a given quantity of radiation.
absorbed dose that amount of energy from ionizing radiations absorbed per unit mass of matter, expressed in rads.
air dose the intensity of an x-ray or gamma-ray beam in air, expressed in roentgens.
booster dose an amount of immunogen (vaccine, toxoid, or other antigen preparation), usually smaller than the original amount, injected at an appropriate interval after primary immunization to sustain the immune response to that immunogen.
curative dose (CD) a dose that is sufficient to restore normal health. See also median curative dose.
divided dose fractionated dose.
effective dose (ED) that quantity of a drug that will produce the effects for which it is administered. See also median effective dose.
erythema dose that amount of radiation that, when applied to the skin, causes erythema (temporary reddening).
fatal dose lethal dose.
fractionated dose a fraction of the total dose prescribed, as of chemotherapy or radiation therapy, to be given at intervals, usually during a 24-hour period.
infective dose (ID) that amount of a pathogenic agent that will cause infection in susceptible subjects. See also median infective dose and tissue culture infective dose.
lethal dose (LD) that quantity of an agent that will or may be sufficient to cause death. See also median lethal dose and minimum lethal dose.
loading dose a dose of medication, often larger than subsequent doses, administered for the purpose of establishing a therapeutic level of the medication.
maintenance dose the amount of a medication administered to maintain a desired level of the medication in the blood.
maximum tolerated dose tolerance dose.
maximum permissible dose the largest amount of ionizing radiation that one may safely receive within a specified period according to recommended limits in current radiation protection guides. The specific amounts vary with age and circumstance.
median curative dose (CD50) a dose that abolishes symptoms in 50 per cent of test subjects.
median effective dose (ED50) a dose that produces the desired effect in 50 per cent of a population.
median infective dose (ID50) that amount of pathogenic microorganisms that will produce demonstrable infection in 50 per cent of the test subjects.
median lethal dose (LD50) the quantity of an agent that will kill 50 per cent of the test subjects; in radiology, the amount of radiation that will kill, within a specified period, 50 per cent of individuals in a large group or population.
median tissue culture infective dose (TCID50) that amount of a pathogenic agent that will produce infection in 50 per cent of cell cultures inoculated.
minimum lethal dose
1. the amount of toxin that will just kill an experimental animal.
2. the smallest quantity of diphtheria toxin that will kill a guinea pig of 250-gm weight in 4 to 5 days when injected subcutaneously.
reference dose an estimate of the daily exposure to a substance for humans that is assumed to be without appreciable risk; it is calculated using the no observed adverse effect level and is more conservative than the older margin of safety.
skin dose (SD)
1. the air dose of radiation at the skin surface, comprising the primary radiation plus backscatter.
2. the absorbed dose in the skin.
threshold dose the minimum dose of ionizing radiation, a chemical, or a drug that will produce a detectable degree of any given effect.
threshold erythema dose (TED) the single skin dose that will produce, in 80 per cent of those tested, a faint but definite erythema within 30 days, and in the other 20 per cent, no visible reaction.
tissue culture infective dose (TCID) that amount of a pathogenic agent that will produce infection when inoculated on tissue cultures; used with a numeric qualifier.
tolerance dose the largest quantity of an agent that may be administered without harm. Called also maximum tolerated dose.

dose

(dōs), Do not confuse this word with dosage.
1. The quantity of a drug or other remedy to be taken or applied all at one time or in fractional amounts within a given period.
See also: dosage (3). Compare: dosage (2).
2. nuclear medicine amount of energy absorbed per unit mass of irradiated material (absorbed dose).
See also: dosage (3).
[G. dosis, a giving]

dose

(dōs)
n.
1.
a. A specified quantity of a therapeutic agent, such as medicine, prescribed to be taken at one time or at stated intervals.
b. The amount of radiation administered as therapy to a given site.
2. Slang A venereal infection.
tr.v. dosed, dosing, doses
1. To give (someone) a dose, as of medicine.
2. To give or prescribe (medicine) in specified amounts.

dos′er n.

dose

The amount of drug administered to a subject/patient at one time, or the total quantity administered.

dose

A quantity of a substance, medication, or radiation that is administered or absorbed during a specific time period Occupational medicine The total amount of a toxicologically relevant material reaching the target site over a specific time period; determination of dose requires information on the agent, its concentration, the form of the agent–eg aerosol, topical, ingested, length of exposure, and weight of person exposed. See MSDS Radiation oncology The concentration of energy divided by the tissue mass of energy deposited by radiation in the body, measured in grays–formerly, rads. See Effective dose, Gray Therapeutics The amount of medicine taken. See Absorbed dose, Effective dose, Equivalent dose, Genetically significant dose, Imputed dose, Law of infinitesimal dose, Lethal dose, Loading dose, Maintenance dose, Maximum tolerable dose, Median lethal dose, Minimum lethal dose, Occupational dose, Organ dose, Overdose, Pharmacologic dose, Ramped dose, Reference dose, TCID.

dose

(dōs)
1. The quantity of a drug or other remedy to be taken or applied all at one time or in fractional amounts within a given period. usage note Sometimes incorrectly used fordosage.
Compare: dosage (2)
2. nuclear medicine Amount of energy absorbed per unit mass of irradiated material (absorbed dose).
See also: dosage
3. radiation therapy The energy absorbed per unit mass of irradiated material.
[G.dosis, a giving]

dose

1. A stipulated quantity of a drug to be taken once or at stated intervals.
2. The amount of radiation received or administered.

dose

the known amount of chemical or other treatment received by an organism.

dose

(dōs) Do not confuse this word with dosage.
Quantity of drug or other remedy to be taken or applied at once or in fractional amounts within a given period.
[G. dosis, a giving]

Patient discussion about dose

Q. dose it ever get better? Dose the feeling of useing ever go away?

A. Well to answer you question bluntly, no they never go away. It just gets easier to say no. I still want to use everyday and I have been clean for 4 years. I still have using dreams. The hard days are when you try to tell yourself that all your problems would go away if you could just get high one more time. what one more time gonna hurt?.....Everything....drugs are way to escape or make you feel like someone your not. my biggest hurdle was really looking at myself and then forgiving myself for all the pain my addiction caused. Everyone has their bottom. Everytime you want to use, put yourself back at that bottom. you will come to realize that life has been patiently waiting for you. The darkness will will fade and you will find your place. Good luck to you I hope you find strength will come in time.

Q. how long dose costochondritis last

A. a friend of mine who had the disease saw an improvement within a few weeks, and it resolved completely within a few months,but his doctor said there are patients in whom this problem persists for some time. All symptoms of pain should resolve within six months.

Q. hemorroid stapling dose any one know about this first hand,or had it done themself? mail me if you have!Thanks Hi, I will have this done on 8/4 . I do need to have some info. about it from someone who has had it done what I need to know before hand!HOW MUCH PAIN, BLEEDING ect. Drs can only tell you so much because they do the surgery but not had it done themself. Please let me know soon, Please!

A. I haven't had it done first hand but I do know from people who have done it that it can hurt in the first few days after and there will be slight bleeding, however that is expected decrease dramatically and make the bleeding eventually stop.

More discussions about dose
References in periodicals archive ?
For a given degree of tumor-cell killing, the delivery of multiple small doses of radiation (fractionation) carries a lower risk of late complications than does the delivery of a single large dose.
Low-dose budesonide with the addition of an increased dose during exacerbations is effective in long-term asthma control.
Table 1 Typical Patient Doses From Various Radiologic Examinations(7)
A mechanism is needed for the determination of radiation doses received by the patients during routine radiological exams with the standard radiographic techniques and at various depths.
"Reduced dose schedules could make vaccination easier to implement and more affordable, creating the potential for higher vaccination coverage and improved cervical cancer protection," they said.
"The flexibility around the timing of the second dose, giving the option of annual vaccination over 2 consecutive years, is an added benefit [because] reduced dose schedules of HPV vaccines may facilitate vaccination implementation and reduce cost, allowing for higher vaccination coverage and potentially more girls being protected from cervical cancer," the investigators noted.
ISO has been the mainstay of acne treatment for more than three decades, and the cumulative experience suggests that daily dose, duration of therapy and cumulative dose are the three factors important in ISO treatment for acne; but due to inconsistent study designs, classification of acne, follow-up periods and definitions of relapse in different studies, the opinion about the optimum dose of ISO and duration of treatment remains divided.
Moore cites the above story, based on actual events, as an important reason for implementing dose monitoring solutions to ensure patient safety but also to help educate patients and referring physicians.
Researchers compared the effectiveness of two doses of vaccine versus one dose and found the effectiveness of one dose was 86 percent, compared to 98.3 percent for two doses.
In the United States, every clinical trial involving these agents has switched to a 40-mg dexamethasone dose once per week as opposed to more frequent dosing, which produces a higher cumulative dose.
Alem dos tratamentos com diferentes doses de N e K, foram aplicados 100 kg [ha.sup.1] de [P.sub.2][O.sub.5] (50 % em area total e incorporado e 50% no plantio, como superfosfato simples); 4,0 kg [ha.sup.-1] de Zn (no plantio, como sulfato de Zn) e 3,0 kg [ha.sup.-1] de B (no plantio, como borax).