dose dependence

Concentration dependence Therapeutics The change in certain pharmacokinetic parameters–clearance, half-life, bioavailable fraction–as a function of administered dose

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12] These inhibitors are thought to produce adverse secondary effects with similar frequency, severity, and dose dependence, but further studies are required to confirm the incidence of adverse events, especially in relation to the lesser prescribed vardenafil and tadalafil.

Sildenafil can induce the onset of a cluster headache bout

Research shows that various components of the placebo effect -- for example, the paraphernalia of care (pills and syringes) and the patient-provider relationship -- can be added incrementally in a manner analogous to dose dependence (the higher the dose, the greater the effect).

Inside the Placebo Effect

The NPL/Harwell data display significant dose dependence for the TC values and TC curve shapes.

Both dosimetry systems exhibit a small dose dependence in the measured temperature coefficient (Table 1).

A comparison of Harwell & FWT alanine temperature coefficients from 25 [degrees]C to 80 [degrees]C

He speculated that it may be an issue of dose dependence, based on data from the phase II RE-DEEM study of dabigatran in patients with acute coronary syndrome.

Dabigatran curbs bleeding in VTE prophylaxis

Strongly superlinear dose dependence of thermoluminescence in synthetic quartz.

Variation on luminescence effect of natural quarts extracted form vellar river seidements

This objective required fulfillment of numerous criteria: low background with no interference from endogenous hormone, robust and statistically significant responses, dose dependence, and low threshold.

A rapid, physiologic protocol for testing transcriptional effects of thyroid-disrupting agents in premetamorphic xenopus tadpoles

Additionally, the technique does not always show dose dependence in an extensive concentration range of analytes, exemplified by the so called high-dose hook effect (3).

Reflectometry interference spectroscopy in detection of hepatitis B surface antigen

Northern analysis was used to confirm that HDI increased message levels of these four genes and to further explore the dose dependence and kinetics of the response.

To facilitate investigations on the dose dependence and kinetics of HDI's effects on human airway epithelial cells, we developed and characterized an in vitro exposure system.

Effects of hexamethylene diisocyanate exposure on human airway epithelial cells: in vitro cellular and molecular studies. (Articles)

Is there a dose dependence for acrolein associated with adduct formation?

1,[N.sup.2]-Propanodeoxyguanosine Adduct Formation in Aortic DNA Following Inhalation of Acrolein

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