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a carbonic acid anhydrase inhibitor, used in treatment of open-angle glaucoma and ocular hypertension; administered topically to the conjunctiva as the hydrochloride salt.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
dorzolamideA CARBONIC ANHYDRASE inhibitor drug used in the form of eyedrops to treat open angle GLAUCOMA. A brand name is Trusopt.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
carbonic anhydrase inhibitors
Drugs which inhibit the carbonic anhydrase enzyme in the ciliary epithelium of the ciliary body. This enzyme is essential for the formation of aqueous humour; its reduction results in a decrease in intraocular pressure. Those in use are sulfonamide derivatives. They are administered systemically (e.g. acetazolamide) or topically in the treatment of glaucoma. Examples: acetazolamide, brinzolamide, dichlorphenamide, dorzolamide.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann