dorsal horn

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Related to dorsal horn: ventral horn, substantia gelatinosa, dorsal root ganglion

dorsal horn

The main column of neuron cell bodies and unmyelinated cell processes (ie, gray matter) running through the dorsal quadrant of each half of the spinal cord. In stained cross-sections of spinal cord, the gray matter forms the rough shape of a butterfly; the dorsal horns are the upper wings.

Synonym: posterior horn See: spinal cord

See also: horn

References in periodicals archive ?

At present, research on the mechanism of neuropathic pain has mainly focused on the peripheral mechanism and the central mechanism, with the central mechanism expressed as changes in synaptic plasticity in the spinal dorsal horn, that is, central sensitization.

Influence of Phosphatidylinositol-3-Kinase/Protein Kinase B-Mammalian Target of Rapamycin Signaling Pathway on the Neuropathic Pain Complicated by Nucleoside Reverse Transcriptase Inhibitors for the Treatment of HIV Infection

Consistent with previous studies, we found that spinal TSPO was upregulated in the dorsal horn after CCI.

Koumine Attenuates Neuroglia Activation and Inflammatory Response to Neuropathic Pain

[GABA.sub.B] receptors are G protein-coupled metabotropic receptors which are widely distributed in the central nervous system, especially in the spinal cord dorsal horn [45].

Activation of [GABA.sub.B] Receptor Suppresses Diabetic Neuropathic Pain through Toll-Like Receptor 4 Signaling Pathway in the Spinal Dorsal Horn

Following the manufacturer's protocol, total RNA was isolated from homogenized ipsilateral L4-L6 spinal dorsal horns using the TRIzol reagent (Invitrogen Corp., Carlsbad, CA, USA).

Low-Concentration Oxygen/Ozone Treatment Attenuated Radiculitis and Mechanical Allodynia via PDE2A-cAMP/cGMP-NF-[kappa]B/p65 Signaling in Chronic Radiculitis Rats

(24, 26) We have shown that BDNF may cause downregulation of the chloride transporter KCC2 in a subpopulation of lamina I secondary sensory neurons in dorsal horn, which then causes a depolarizing shift in the anion reversal potential ([E.sub.anion]).

Purinergic signaling in microglia in the pathogenesis of neuropathic pain

Todd, "Neuronal circuitry for pain processing in the dorsal horn," Nature Reviews Neuroscience, vol.

Neurobiological Mechanism of Acupuncture for Relieving Visceral Pain of Gastrointestinal Origin

Glial Cell Profiling in the Dorsal Horn of Rats with 8 Weeks of Experimental Diabetes.

Neutrophils Infiltrate the Spinal Cord Parenchyma of Rats with Experimental Diabetic Neuropathy

Carstens, "Role of TNF-alpha in sensitization of nociceptive dorsal horn neurons induced by application of nucleus pulposus to L5 dorsal root ganglion in rats," Pain, vol.

Hyperexcitability in Spinal WDR Neurons following Experimental Disc Herniation Is Associated with Upregulation of Fractalkine and Its Receptor in Nucleus Pulposus and the Dorsal Root Ganglion

Roberts, "Anterior pretectal nucleus facilitation of superficial dorsal horn neurones and modulation of deafferentation pain in the rat.," The Journal of Physiology, vol.

Electroacupuncture Inhibits the Activation of p38MAPK in the Central Descending Facilitatory Pathway in Rats with Inflammatory Pain

Henry, "Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: Results with indomethacin in the rat in vivo," Neuroscience, vol.

Preemptive Analgesic and Antioxidative Effect of Curcumin for Experimental Migraine

SNI induced a robust astrocytic activation, indicated by GFAP upregulation in the ipsilateral spinal dorsal horn of SNI group (Fig.

Analgesic effect of total flavonoids from Sanguis draxonis on spared nerve injury rat model of neuropathic pain