dorsal horn


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

dorsal horn

The main column of neuron cell bodies and unmyelinated cell processes (ie, gray matter) running through the dorsal quadrant of each half of the spinal cord. In stained cross-sections of spinal cord, the gray matter forms the rough shape of a butterfly; the dorsal horns are the upper wings.
Synonym: posterior horn See: spinal cord
See also: horn
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
At present, research on the mechanism of neuropathic pain has mainly focused on the peripheral mechanism and the central mechanism, with the central mechanism expressed as changes in synaptic plasticity in the spinal dorsal horn, that is, central sensitization.
Consistent with previous studies, we found that spinal TSPO was upregulated in the dorsal horn after CCI.
[GABA.sub.B] receptors are G protein-coupled metabotropic receptors which are widely distributed in the central nervous system, especially in the spinal cord dorsal horn [45].
Following the manufacturer's protocol, total RNA was isolated from homogenized ipsilateral L4-L6 spinal dorsal horns using the TRIzol reagent (Invitrogen Corp., Carlsbad, CA, USA).
(24, 26) We have shown that BDNF may cause downregulation of the chloride transporter KCC2 in a subpopulation of lamina I secondary sensory neurons in dorsal horn, which then causes a depolarizing shift in the anion reversal potential ([E.sub.anion]).
Todd, "Neuronal circuitry for pain processing in the dorsal horn," Nature Reviews Neuroscience, vol.
Glial Cell Profiling in the Dorsal Horn of Rats with 8 Weeks of Experimental Diabetes.
Carstens, "Role of TNF-alpha in sensitization of nociceptive dorsal horn neurons induced by application of nucleus pulposus to L5 dorsal root ganglion in rats," Pain, vol.
Roberts, "Anterior pretectal nucleus facilitation of superficial dorsal horn neurones and modulation of deafferentation pain in the rat.," The Journal of Physiology, vol.
Henry, "Mediation and modulation by eicosanoids of responses of spinal dorsal horn neurons to glutamate and substance P receptor agonists: Results with indomethacin in the rat in vivo," Neuroscience, vol.
SNI induced a robust astrocytic activation, indicated by GFAP upregulation in the ipsilateral spinal dorsal horn of SNI group (Fig.