dopamine transporter


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dopamine transporter (DAT),

a protein, found, for example, in the terminal of a presynaptic neuron, which decreases the concentration of dopamine near the synapse by effecting its reuptake into the presynaptic neuron.
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References in periodicals archive ?
Association of dopamine transporter loss in the orbitofrontal and dorsolateral prefrontal cortices with methamphetamine-related psychiatric symptoms.
A Comparison Study of Working Memory Deficits between Patients with Methamphetamine-Associated Psychosis and Patients with Schizophrenia
Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding.
Asociacion entre dopamina serica y colesterol total en caninos
Niznik, "Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis," FASEB Journal, vol.
The Sources of Reactive Oxygen Species and Its Possible Role in the Pathogenesis of Parkinson's Disease
[24] Parkinson Study Group, "Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression," JAMA, vol.
Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling
Lack of association between the dopamine transporter gene 3' VNTR polymorphism and attention deficit hyperactivity disorder in Chinese Han children: case-control and family-based studies.
Estudio de variantes de los genes BDNF, COMT, DAT1 y SERT en ninos colombianos con deficit de atencion
Immunohistochemistry Assays for Tyrosine Hydroxylase (TH) and Dopamine Transporter (DAT) in Striata.
The Treadmill Exercise Protects against Dopaminergic Neuron Loss and Brain Oxidative Stress in Parkinsonian Rats
Hall et al., "Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: Prominent effects of dopamine transporter deletions," Behavioural Pharmacology, vol.
The Role of MAPK and Dopaminergic Synapse Signaling Pathways in Antidepressant Effect of Electroacupuncture Pretreatment in Chronic Restraint Stress Rats
Nonclassical pharmacology of the dopamine transporter: atypical inhibitors, allosteric modulators, and partial substrates.
Developing treatments for stimulant abuse: a brief overview
Dopamine transporter occupancies in the human brain induced by therapeutic doses of oral methylphenidate.
What does molecular imaging reveal about the causes of ADHD and the potential for better management? Dysfunction of dopaminergic-frontostriatal neural circuits appears central in ADHD
In this study, we aimed to assess the function of presynaptic dopaminergic neurons in patients with mRT by dopamine transporter positron emission tomography (DAT-PET) and to evaluate the utility of clinical features or electrophysiological studies in differential diagnosis.
Heterogeneity of Monosymptomatic Resting Tremor in a Prospective Study: Clinical Features, Electrophysiological Test, and Dopamine Transporter Positron Emission Tomography
Nihon Medi-Physics markets the brain disorder diagnostic agent DaTSCAN Injectable (ioflupane [123I], "DaTSCAN"), which is the only product indicated for the use of dopamine transporter scintigraphy in diagnosing DLB in Japan.
Eisai and Nihon Medi-Physics Enter Collaboration Agreement to Contribute to Diagnosis and Treatment of Dementia with Lewy Bodies
The dopamine transporter (DAT) belongs to the SLC6A family of secondary-active [Na.sup.+]/Cl-dependent neurotransmitter transporters and functions to terminate dopaminergic signaling through re-uptake of dopamine (DA) from the synapse (1-3) (1).
Cocaine photo-affinity analogs bind in the substrate binding pocket of the dopamine transporter

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