dominance of traits

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Related to dominant inheritance: codominant inheritance

dom·i·nance of traits

an expression of the apparent physiologic relationship existing between two or more genes that may occupy the same chromosomal locus (alleles). At a specific locus there are three possible combinations of two allelic genes, A and a: two homozygous (AA and aa) and one heterozygous (Aa). If a heterozygous individual presents only the hereditary characteristic determined by gene A, but not a, A is said to be dominant and a recessive; in this case, AA and Aa, although genotypically distinct, should be phenotypically indistinguishable. If AA, Aa, and aa are distinguishable, each from the others, A and a are codominant.

dom·i·nance of traits

(dom'i-năns trāts)
An expression of the apparent physiologic relationship existing between two or more genes that may occupy the same chromosomal locus (alleles). At a specific locus there are three possible combinations of two allelic genes, A and a: two homozygous (AA and aa) and one heterozygous (Aa). If a heterozygous individual presents only the hereditary characteristic determined by gene A, but not a, A is said to be dominant and a recessive; in this case, AA and Aa, although genotypically distinct, should be phenotypically indistinguishable. If AA, Aa, and aa are distinguishable, each from the others, A and a are codominant.
References in periodicals archive ?
They concluded that AHDC1 haploinsufficiency caused the XGS (MIM #615829), a rare syndromic form of ID with autosomal dominant inheritance. AHDC1 is located on 1p36.11 and encodes a protein of 1603 amino acids.
A Three-generation family with idiopathic facial palsy suggesting an autosomal dominant inheritance with high penetrance.
The genogram (Figure 3) suggests an autosomal dominant inheritance with maternal derived transmission.
In this study, we found that, in dominant inheritance model, the carriers of T/T or T/C of rs2291725 had lower CAD risk compared to C/C carriers.
NF1 often follows an autosomal dominant inheritance pattern, although up to 50% of patients with NF1 arise de novo from spontaneous mutations.
However, in dominant inheritance, generation skipping may occur due to non-penetrance (Fig.
Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes with autosomal dominant inheritance and usually develops before 25 years.
Family members affected in three generations have bilateral cataracts, hyperferritinemia and an autosomal dominant inheritance pattern.
While in Mibelli disease the autosomal dominant inheritance is related to metabolic diseases, such as angiokeratoma corporis diffusum, also called Fabry disease, no such relation exists in Fordyce angiokeratoma.
The condition was initially described in Japanese patients, where it is still most common, in which 7-10% of cases are familial with autosomal dominant inheritance pattern.
Among the 33 FPD patients, 29 had dominant inheritance (DFPD), 2 had recessive inheritance (RFPD), and in 2 patients the mode of inheritance could not be specified (parents were consanguineous and one of them is with PD).
The etiology and pathogenesis remain unclear but, studies have identified several risk factors for the development of porokeratosis including genetic inheritance (an autosomal dominant inheritance pattern with incomplete penetrance), immunosuppression, ultraviolet radiation and trauma [3, 4].