dobutamine


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dobutamine

 [do-bu´tah-mēn]
a synthetic catecholamine administered parenterally as the hydrochloride salt for inotropic support in short-term treatment of adults with cardiac decompensation due to depressed contractility resulting either from organic heart disease or from cardiac surgical procedures.

dobutamine

Cardiology A β—agonist used to treat standard therapy-refractory acute CHF; in contrast to other beta agonists, e.g., isoproterenol, dobutamine is not associated with a ↑↑↑ in myocardial O2 consumption–MOC, which precluded their use; dobutamine has only moderate vasodilating activity, ↑ cardiac output with little change in MOC. See Vascular-Ventricular coupling.

dobutamine

A drug used to assist in the management of HEART FAILURE. It increases the force of the contraction (inotropic agent) of the muscle of the ventricles and improves the heart output. It may be given by continuous intravenous drip. Brand names are Dobutrex and Posiject.
References in periodicals archive ?
No intervention (volume expansion, [11] dopamine, dobutamine, [12] adrenaline [13]) has been shown to positively affect short-term outcomes, despite these remaining the most common interventions in neonatal hypotension.
The study included 560 consecutive patients with cirrhosis and end-stage liver disease who were awaiting a liver transplant at the Victoria Liver Transplant Unit in Melbourne and underwent assessment by stress echocardiography using low-dose dobutamine (10 meg/kg per min) during 2010-2017 as part of their standard pretransplant work-up.
Group G adopted the GDFT programme: When the CI was in 2.5-4.0 L.min-1.m-2 and SVV4.0 L.min-1.m-2, controlled the speed of infusion and used vasodilators or appropriately adjusted the depth of anesthesia according to the BIS value; When the CI <2.5 L.min-1.m-2 and SVV<13%, took advantage of dobutamine; When CI13%, 6% hydroxyethyl starch injection 130/0.4 250ml was infused in 5~15 minutes.
He added: "What is clear is that any suggestion of an error involving an overdose of the drug dobutamine can be clearly ruled out as a contributing factor."
Additionally, the center's non-invasive cardiac care diagnostics services cover 24-hour blood pressure monitoring; coronary catheterization; EKG-ECG; external event recording; stent follow-up; 24-hour Holter monitoring; Dobutamine Stress echocardiography; Ex-ECG (TMT); congestive heart failure diagnosis & management, complete executive physicals; exercise stress test, cholesterol treatment, Ankle Brachial Index, Carotid & peripheral Doppler.
(NASDAQ: TENX) is touting the results of a new study titled "Differential Effects of Levosimendan and Dobutamine on Glomerular Filtration Rate in Patients With Heart Failure and Renal Impairment: A Randomized Double-Blind Controlled Trial" were published in the August 21, 2018 issue of the Journal of the American Heart Association.
Tenax Therapeutics announced the results of a new study titled "Differential Effects of Levosimendan and Dobutamine on Glomerular Filtration Rate in Patients With Heart Failure and Renal Impairment: A Randomized Double-Blind Controlled Trial" were published in the August 21, 2018 issue of the Journal of the American Heart Association.
The additional cardiology tests are: | Blood Pressure Monitoring | Heart Rhythm Recording | Cardiac Computed Tomography (Cardiac CT) | Cardiac Magnetic Resonance Imaging (Cardiac MRI) | Dobutamine Stress Echocardiogram (DSE) | Myocardial Perfusion Scanning | Diagnostic Angiography | Diagnostic Electrophysiology (EP Study) | Trans Oesophageal Echocardiogram (TOE)
They said some of the unavailable life-saving medicines included Dopamine, Dobutamine, Norpine, IV fluids, Atem and Clenil for nebulization while IV line, nasal prong, vitamin K, 1-CC syringes are also not available in paediatric and neonatal emergency wards of the hospital.
Moreover, due to the low ventricular contractility, additional dobutamine at 3 [micro]g/kg/min was initiated.
Myocardial ischemia can be identified by metabolic alterations detected with PET imaging, perfusion defect reversibility detected by CMR with adenosine/Lexisan, dipyridamole or dobutamine, regional wall motion abnormalities seen by echocardiography and CMR, or ECG changes detected by standard stress test treadmill.