dithranol


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dithranol

A drug used in the treatment of PSORIASIS. It is an ANTIMITOTIC agent and acts to discourage overgrowth of epidermal cells. The drug is on the WHO official list. Brand names are Dithrocream, Micanol, Psorin ointment and Psorin scalp gel.
References in periodicals archive ?
Dithranol can be used in different type of alopecia areata as contact irritant.
On the other hand, dithranol should be used with caution due to potential irritation.
Other types of topical treatments include keratolytics, calcipotriol, calcipotriol with betamethasone dipropionate, and dithranol (Table 2).
Other antiplaque topical medications include salicylic acid, dithranol and calcipotrol.
Moreover, LNC have shown capacity to encapsulate topical corticosteroids with mometasone furoate, suitable for prolonged treatment of skin disorders [36], dexamethasone, promoted increase of drug delivered into viable epidermis [37], betamethasone dipropionate, and dithranol, and provided decreased irritation potential of these drugs [38, 39].
Other options available for limited patchy AA are potent topical corticosteroids, dithranol and minoxidil lotion.
In general, initial treatment of psoriasis involves application of a topical medicine, which could be a steroid preparation, retinoid (synthetic vitamin A), dithranol, calcipotriol (a vitamin D analog), anthralin, or coal tar.
Further 5 [micro]L of SLJO sample was mixed with 20 [micro]L of dithranol matrix and MALDI-MS study was done on AB SCIEX TOF/TOF 5800.
MALDI-TOF mass spectra were obtained using a MICROFLEX LT (Bruker) with dithranol (DHB) or trans-2-[3-(4-tert-Butylphenyl)-2-methyl-2-propenylidene]malononitrile (DCTB) as matrix.
Many therapeutic modalities are available for the treatment of Psoriasis both topical and systemic including salicylic acid, corticosteroids, tar, dithranol and ultraviolet B (UVB), and systemic agents like photochemotherapyretinoids, methotrexate and cyclosporine.4 The choice of therapy is determined by many factors, like age, sex, site, severity and duration of disease and general health of the patient.
Concurrent pharmacotherapies could include: emollients, corticosteroids, vitamin D3 analogues, tazarotene, coal tar, dithranol, methotrexate (MTX), cyclosporine, retinoids, fumarates and/or biological agents.
CsA and dithranol used concurrently produce benefits in a subset of patients described by Gottlieb et al.