distomer

distomer

(dis'tō-mĕr),
The enantiomer or stereoisomer with the lesser activity at or affinity for a given receptor, one receptor's distomer can be another receptor's eutomer.
See also: enantiomer.

distomer

(dis'to-mer)
Of two enantiomeric compounds, the one with the weaker chemical activity.
See: eutomer.
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References in periodicals archive ?
The inactive isomer (distomer) has been discarded in the hope of eliminating or reducing potential unnecessary side effects.
Development and Validation of an Ultra Performance Liquid Chromatography Method for the Determination of Dexketoprofen Trometamol, Salicylic Acid and Diclofenac Sodium/Deksketoprofen Trometamol, Salisilik Asit ve Diklofenak Sodyum Etkin Maddeleri icin Ultra Performansli Sivi Kromatografisi Yonteminin Gelistirilmesi ve Validasyonu
(a) Analgesics Chirality Sample Salicylate NA (b) Serum, plasma (Acetylsalicylic acid) (heparin or EDTA), urine, saliva, synovial fluids Diflunisal NA Serum or plasma Acetaminophen NA Serum/plasma (EDTA), (g) urine, CSF (S)-(+)-Ibuprofen Eutomer Serum, plasma, (R)-(-)-Ibuprofen Distomer urine (S)-(+)-Naproxen Eutomer Serum, plasma, urine (+/-)-Tramadol ?
Standards of laboratory practice: analgesic drug monitoring
Hyper -responsiveness of the airways to histamine following exposure of guinea pigs to racemic mixtures and distomers of P2-selective sympathomimetics.
Comparative evaluation of clinical efficacy and safety of salbutamol and Levosalbutamol MDI in patients of Bronchial asthma

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