disruption sequence

disruption sequence

Pediatrics The constellation of malformations that occur when a normally developing fetus is subjected to a toxin–eg, thalidomide or pathogen–eg, rubella
References in periodicals archive ?
In patients without collagenopathies, mutations in the genes GDF3 and GDF6 which code for osseous growth differentiation factors, defects of postotic neural crest (PONC) cells, or subclavian artery supply disruption sequence (SASDS) have been proposed as explanations for the anomalies previously listed [7-9].
Weaver, "Subclavian artery supply disruption sequence: hypothesis of a vascular etiology for Poland, Klippel-Feil, and Mobius anomalies," American Journal of Medical Genetics, vol.
The main reported signs and symptoms include abnormalities in neurologic examination, dysphagia, microcephaly (7-9), and a phenotype characterized as fetal brain disruption sequence (10).
In total, 64.5% of infants were born with severe microcephaly, and 95.8% had a phenotype of fetal brain disruption sequence.
Therefore, screening should be based not only on HC measurement at birth but also on the phenotype associated with fetal brain disruption sequence and cranial CT scan imaging findings.
The Brazilian outbreak of Zika virus has been linked with a particularly devastating form of microcephaly known as fetal brain disruption sequence. Until Zika spread to Brazil, only a handful of fetuses with that condition had been recorded.
The Brazilian outbreak of Zika virus has been linked with a particularly devastating form of microcephaly known as foetal brain disruption sequence. Until Zika spread to Brazil, only a handful of foetuses with that condition had been recorded.
This critical vascular event known as subclavian artery supply disruption sequence (SASDS), occurs when the medial and forward growth of the ribs forces the subclavian vessel into a U-shaped configuration.
Common mechanisms for Chiari malformations and Klippel-Feil syndrome have been previously proposed; i.e., defects of postotic neural crest (PONC) cells and subclavian artery supply disruption sequence (SASDS) have been hypothesized as common explanations for Klippel-Feil syndrome and Moebius syndrome [8, 9].
Constrictive amniotic bands, amniotic adhesions, and limb body wall complex: discrete disruption sequences with pathogenic overlap.