DVL2

(redirected from dishevelled 2)

DVL2

A gene on chromosome 17p13.1 that encodes a member of the Dishevelled (Dsh) protein family which undergoes post-translational phosphorylation and may play a role in the Wnt signal transduction pathway.
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From more than 12 million individual differences, they identified one mutation, in a gene called "Dishevelled 2," or DVL2, that was found in all the bulldogs and French bulldogs sampled.
Mansour, TA, et al, Whole genome variant association across 100 dogs identifies a frame shift mutation in DISHEVELLED 2 which contributes to Robinow-like syndrome in Bulldogs and related screw tail dog breeds.