Sontags team has developed a multilayer probabilistic
disease progression model that relates a continuous disease state to the comorbidities discretely observed in EHR.
194 additional QALYs, compared with esophagectomy upon
disease progression to cancer, assuming a 0.
Regardless of the endometriosis stage at first laparoscopy, there were no statistical trends toward
disease progression, but a significant likelihood (especially in patients with stage II or III disease) of improvement in endometriosis by the second surgery.
Research on the possible relationship between hormonal contraception and HIV
disease progression is hampered by the same methodological challenges facing studies of hormonal contraceptive use and the risk of HIV acquisition or transmission (see articles, pages 5 and 14).
Whether these risk factors reflect an increased risk for tuberculous infection or an increased risk for
disease progression is not clear, however.
Also, if we understood how depression and anxiety (the biochemical changes that are most easily recognized by their mental effects) act to speed
disease progression, we might find new mechanisms for pharmaceutical intervention to slow disease development and increase overall health.
An important point to also consider is that interferon has certain properties that allow it to slow down liver
disease progression even if the viral load is not reduced.
The link between stable partnerships and slower
disease progression in this study could be related to drug adherence or lower rates of depression in those with a stable partner, they speculated.
RAPID
DISEASE PROGRESSION FOLLOWING ACUTE INFECTION BY POLYTROPIC HIV-1.
Approved November 17, 1995 for the treatment of Kaposi's sarcoma in AIDS patients who are intolerant to or have
disease progression on prior combination chemotherapy.
The ISCTM meeting Advances in the Conceptualization of
Disease Progression in Alzheimer's Disease-An Interdisciplinary Conference, will prove an immensely valuable follow up to ICAD for scientists, clinical trialists, pharmaceutical industry and regulatory authorities worldwide who are trying to make our research endeavors more efficient and effective.
The recommended dose of Keytruda in adults is 200 mg administered as an intravenous infusion over 30 minutes every three weeks until
disease progression, unacceptable toxicity, or up to 24 months in patients without
disease progression.
