Of the 92 patients studied, 66 (71.7%) did not have any autoimmune disease marker
, 25 (27.2%) had one autoimmune disease marker
, and one (1.1%) had two autoimmune disease markers
The findings of present study could be replicated in a bigger multiracial study cohort to identify ethnicity specific disease marker
for timely diagnosis, management, and treatment of disease.
A structural analysis of cutaneous denervation in a population of PD patients has displayed a link between [alpha]-synuclein deposition in autonomic small fibers and severity of clinical symptoms related to autonomic dysregulation such as orthostatic hypotension or sweating disturbances, indicating the usefulness of skin pathology as potentially valid disease marker
Claims reciting using an agent to detect a disease marker
, but where the agent was not narrowly specified (e.g., "a labelled probe" rather than the narrower "a labelled probe having SEQ ID NO:1"), accounted for 18 of the reviewed 2016 patents.
One potential limitation of myeloperoxidase as an inflammatory marker is its cationic charge, which may lead it to bind to fecal particles, limiting reliability as a disease marker
The most encouraging of these is NT-proBNP, a circulatory disease marker
. Easily done in conjunction with a routine blood profile, NT-proBNP could be the best demarcator ever for assessing atherosclerotic disease risk.
The women underwent brachial artery ultrasound to assess brachial artery flow-mediated dilation (FMD), a preclinical disease marker
that has been linked to clinical outcomes.
The biosensors are based on optical detection of a change in spectral response of the nanostructures upon binding a disease marker
. The detection sensitivity can be increased by changing the morphology and size of the noble metal nanostructures.
Koroshetz suggests that the long-sought Huntington's disease gene may encode a mitochondrial protein, but he cautions that no gene involved in energy production has yet been discovered near the Huntington's disease marker
on chromosome 4.
Patients with CD often have high circulating concentrations of anti-endomysium antibodies (EMAs), the main disease marker
(5), and anti-gliadin antibodies (AGAs), the most effective marker for children <3 years (6,7).
A promising disease marker
, recently identified by Dr.
"The use of a disease marker
, levels of HIV RNA in patients' blood, played a key role in the development of the current highly effective therapies for AIDS that have made a vast difference in the survival and quality of life of HIV-infected individuals", said William E.