generally) why would a discordant couple
use PrEPs when antiretrovirals with condoms pretty much do the trick?
Negative people enjoy sex, but the discordant couple
does not enjoy sex because of a condom.
In the HIV Prevention Trials Network 052 study of discordant couples
, for instance, early antiretroviral therapy in an infected partner not only reduced the number of clinical events; it almost completely blocked sexual transmission of the virus to an HIV-negative partner (N.
The data come from HIV discordant couples
enrolled in ZEHRP as part of IAVI's Protocol C (http://www.
There is a clear transmission-prevention benefit in discordant couples
and there are accumulating data in the community setting.
experiences in preventing HIV infections among discordant couples
will inform current and
There are uncontested reasons for using antiretrovirals (ARVs) treatment of significant HIV-related immunodeficiency, and prevention of transmission of HIV from mother to child and between discordant couples
UNAIDS also estimates that an additional four million discordant couples
-- where one partner is living with HIV -- would benefit from HIV treatment to protect their partners from HIV infection.
A significant reduction in HIV infection in discordant couples
Retention is 96% among the index cases and 85% for the discordant couples
HIV-1 transmission among HIV-1 discordant couples
before and after the introduction of antiretroviral therapy.
Other essays call upon Catholic leaders to revisit what the Church teaches about the use of condoms as a tool for preventing the spread of HIV/AIDS, especially among HIV discordant couples