Third, we recognized that it is not the same to be a woman living with HIV in a discordant couple
than a woman who is the partner of a man who is HIV+.
When the female partner is HIV-infected and the male partner is not, a discordant couple
can undergo autologous sperm intrauterine inseminations to achieve conception without placing the man at risk for infection.
generally) why would a discordant couple
use PrEPs when antiretrovirals with condoms pretty much do the trick?
Negative people enjoy sex, but the discordant couple
does not enjoy sex because of a condom.
A subsequent study using DHS data from 18 countries, the majority in sub-Saharan Africa, found that discordant couple
preferences are common with men often preferring more children and shorter birth intervals than their wives; in 10 to 26% of couples, there was disagreement on desire for additional children (6).
Based on this study, for discordant couples
in which the man is treated with HAART, the postulated risk for transmission to a female partner during condomless intercourse would be 0.
The correct and consistent use of condoms has proven to be effective in preventing HIV transmission between discordant couples
6 In a Ugandan cohort of HIV discordant couples
, the probability of HIV transmission per coital act increased 2-fold in the presence of genital ulcer disease (GUD), whereas there was no increased risk of transmission for non-ulcer syndromes.
Sexual behavior of HIV discordant couples
after HIV counseling and testing.
In the HIV Prevention Trials Network 052 study of discordant couples
, for instance, early antiretroviral therapy in an infected partner not only reduced the number of clinical events; it almost completely blocked sexual transmission of the virus to an HIV-negative partner (N.
There is a clear transmission-prevention benefit in discordant couples
and there are accumulating data in the community setting.