Using these follow-up modalities as the gold standard, discordance
rates were calculated for PGFNAs and UGFNAs.
A deficit in one of these aspects can create a discordant assessment (i.e., iatrogenic discordance
However, the most common aetiology responsible for phenotype discordance
between MZ twins is the involvement of epigenetic mechanisms.
The majority of recorded discordances
occurred in gastrointes tinal, skin, genitourinary, and gynecologic cases.
First, it is a cross-sectional study and therefore cannot predict the development of coronary artery disease, nor can it predict the effects of cholesterol-lowering therapy in the concordance and discordance
In 6 cervical cases, there was a slight discordance
in the grading of dysplasia for the low-grade category, between cervical intraepithelial neoplasia grade 1 (CIN1) and condyloma (cases 5-10); and in 2 cases, discordance
concerned the high-grade lesions (CIN2 versus CIN3/carcinoma in situ; cases 3 and 4).
Our study focused on discordances
in distinguishing NSCLC from SCLC because pathologists have not been asked before to further classify the lung cancer type in cytology specimens.
The aims of this study were (a) to prospectively assess the quality of biopsy in a large hospital-based cohort; (b) to prospectively assess the prevalence and the factors associated with significant discordances
between liver biopsy estimates and FT-AT estimates; (c) to attribute the cause of discordances
to biopsy or to FT-AT; and (d) to detect possible causes of failures attributable to FT-AT in a large community-based population by analyzing the distribution of the six components of FT-AT.
between cTnT and cTnI were observed in 6 of a total of 18 samples in sample I and persisted in 5 of these in sample II at either cutoff value.
Our objective was to determine the rate and degree of growth discordance
in pregnancy with dichorionic twins conceived by IVF compared to those conceived spontaneously and to assess association of the growth discordance
with adverse perinatal outcome.
The use of a validated image-analysis system has been shown to substantially reduce interpathologist discordance
in interpreting IHC assay results (9).
The finding that discordance
is more often explainable by failure of the liver biopsy than by errors in the markers might be considered as evidence that fibrosis markers are more accurate than biopsy.