disaccharidase


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disaccharidase

 [di-sak´ah-ri-dās″]
an enzyme that hydrolyzes disaccharides; in humans the disaccharidases are located in the brush border membrane of the small intestine and hydrolyze the oligosaccharides and disaccharides produced after luminal digestion of starches and other carbohydrates. See also disaccharide intolerance.

disaccharidase

/di·sac·cha·ri·dase/ (di-sak´ah-rĭ-dās″) an enzyme that catalyzes the hydrolysis of disaccharides.

disaccharidase

(dī-săk′ər-ĭ-dăs′, -dāz′)
n.
An enzyme, such as invertase or lactase, that catalyzes the hydrolysis of disaccharides to monosaccharides.

disaccharidase

[disak′äridās′]
in humans, the enzyme that hydrolyzes disaccharides. The disaccharidases are located in the brush border membrane of the small intestine and hydrolyze the oligosaccharides and disaccharides produced after luminal digestion of starches and other carbohydrates. See also disaccharide intolerance.

disaccharidase

any of a group of enzymes which are components of the brush border of the intestinal epithelium and which hydrolyze disaccharides to monosaccharides. They include lactase, maltase, sucrase and galactosidase. Enteric infections may cause a temporary deficiency of lactase leading to the development of an osmotic-type diarrhea. All disaccharidases are not present immediately following birth and feeding sucrose to young calves will result in diarrhea.
References in periodicals archive ?
These non-absorbable disaccharides are hydrolyzed to absorbable monosaccharides by disaccharidase enzymes present in the small-intestinal mucosa.
In some instances, decreased activity of digestive enzymes such as disaccharidases may cause a secondary lactose intolerance and mal-absorption of nutrients.
The findings for Trigonella foenum-graeceum, however, indicate that the furostanol saponins isolated from Balanites aegyptiaca may have more than one potential mechanism of action contributing to the anti-diabetic activity, and that further studies on the disaccharidase and glycogen enzymatic activity modulation would be useful.
The pathophysiology involved is the loss of disaccharidases in these areas and the resulting carbohydrate malabsorption which provides excess substrate for microbial growth.
The effect of severe zinc deficiency on activity of intestinal disaccharidases and 3-hydroxy-3-methylglutaryl coenzyme A reductase in the rat.
1) In addition, a significant reduction in total disaccharidase activity was found in the jejunum of patients with Crohn's disease who had no radiologic evidence of small-bowel involvement.
For determination of the disaccharidase activity 50 [micro]l of homogenate were pre-incubated at 37 [degrees]C for 5 min, in the absence (control) or in the presence of the Et0Ac or n-BuOH fractions of paraguariensis (treated).
Distribution of disaccharidase activity in the small bowel of normal and lactase-deficient subjects.
It is unlikely that these infants had such congenital diarrhoeas as tufting enteropathy, microvillus inclusion disease, glucose-galactose malabsorption, or congenital disaccharidase deficiencies because these entities do not respond to corticosteroid therapy and are not self-limiting.
charantia was also found to lower blood sugar and small intestine disaccharidase activity in rats (Oishi et al.