directly observed therapy

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directly observed therapy (DOT),

visual monitoring by a health care worker of patients' ingestion of medications, to ensure compliance in difficult or long-term regimens, such as in oral treatment for tuberculosis; a contentious aspect of some WHO programs.
Farlex Partner Medical Dictionary © Farlex 2012

directly observed therapy

Therapeutics A strategy for ensuring Pt compliance with therapy, where a health care worker or designee watches the Pt swallow each dose of prescribed drugs. See Patient compliance. Cf Directed observation.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

directly observed therapy



Oral administration of a drug or of drugs to a patient under supervision to ensure the drug is swallowed. DOT is esp. important in treating patients with infectious diseases (e.g., HIV/AIDS or tuberculosis) in which development of drug-resistant microorganisms is likely to threaten public health if the drug is not taken exactly as prescribed.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Directly observed therapy compared with self-administered therapy.
In the population-based prospective study of 436 patients undergoing directly observed therapy, short course (DOTS), three indicators of ongoing TB transmissions showed that transmission declined between 1995 and 2000.
Directly observed therapy (DOT) for tuberculosis: Why, when, how, and if?
Given the severe consequences of poor adherence, health agencies recommend directly observed therapy (DOT), a process in which healthcare workers or trusted designees watch patients swallow each medication dose (8-10).
As a result, JCDHE developed a policy and procedure to allow persons who met eligibility requirements to complete 12 weekly doses of isoniazid and rifapentine treatment using video directly observed therapy (VDOT) rather than traditional in-person directly observed therapy (DOT).
Conclusion: There is a need to fully implement national tuberculosis guidelines with a focus on expansion and effective implementation of directly observed therapy short course in order to prevent further emergence of drug resistance.
One could hypothesize that expedited treatment obligates a type of "directly observed therapy" of infected partners by patients, without which patients may be less likely to engage in sexual relationships with these individuals.
Directly observed therapy, in which someone watches the patient ingest the prescribed dose, is essential in helping patients complete their treatment regimens.
Thus, it lends itself to use as 'directly observed therapy' (DOT) in situations where intermittent oversight by health care professionals is required, or is available.8 All the molecules available as once-weekly preparations have a low risk of hypoglycaemia as well.
Direct observation of treatment (directly observed therapy, or DOT) was 1 of the 5 components of the strategy promoted by the World Health Organization (WHO) and public health advocates to address the global TB emergency declared in the early 1990s (6), (http://

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