diphtheria toxoid


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Related to diphtheria toxoid: diphtheria antitoxin, tetanus toxoid

toxoid

 [tok´soid]
a toxin treated by heat or chemical agent to destroy its deleterious properties without destroying its ability to combine with or stimulate the formation of antitoxin.
diphtheria toxoid a sterile preparation of formaldehyde-treated products of the growth of Corynebacterium diphtheriae, used as an active immunizing agent, generally in mixtures with tetanus toxoid and pertussis vaccine (DTP) or with tetanus toxoid alone (DT for pediatric use and Td, which contains less diphtheria toxoid, for adult use).
tetanus toxoid a sterile preparation of formaldehyde-treated products of the growth of Clostridium tetani, used as an active immunizing agent, either in mixtures with diphtheria toxoid and pertussis vaccine (DTP, DT, Td) or by itself (T).

diphtheria toxoid

Diphtheria toxin altered so that it cannot cause disease but is still able to stimulate the production of antibodies for active immunization. It is used in diphtheria-pertussis-tetanus vaccine (DTaP).
See also: toxoid
References in periodicals archive ?
Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine (Tdap) in pregnant women and persons who have or anticipate having close contact with an infant aged <12 months--Advisory Committee on Immunization Practices (ACIP), 2011.
Still, in our previous study, a doubling of the PCB exposure at 18 months was associated with a decrease in the concomitant antibody response to the diphtheria toxoid by 24%, and the decrease in the tetanus toxoid antibody at age 7 years was 16% for each doubling of the prenatal exposure level (Heilmann et al.
CDC, Preventing Tetanus, Diphtheria and Pertussis Among Adults: Use of Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine.
Issues related to the decennial tetanus diphtheria toxoid booster recommendations in adults.
Tetanus and diphtheria toxoid (Td) vaccination would decrease the risk for recurrence of widespread diphtheria in the United States.
Safety in Concomitant Use with Menactra [Meningococcal (Groups A, C, Y and W-135) Polysaccharide Diphtheria Toxoid Conjugate Vaccine] and Adacel [Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed (Tdap)]
Beginning in 2012, tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccine has been recommended for pregnant women during the third trimester of each pregnancy to provide protection to the newborn.
The technique uses a part of the Haemophilus bacterium that would normally stimulate only a weak immune response (a "hapten') and links it to a potent immune system stimulant, or "carrier' --in this case a protein component of diphtheria toxoid.
5 ml dose of MassBiologics' Td is formulated to contain the following active ingredients: 2 Lf of tetanus toxoid and 2 Lf of diphtheria toxoid.
The company stated the vaccines that will feature the 2D barcode includes Adacel (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed) vaccine; and Fluzone (Influenza Virus Vaccine).
26 April 2011 - Sanofi Pasteur, the vaccines division of French sanofi-aventis (EPA: SAN), said last Friday that the US Food and Drug Administration (FDA) has granted licensure to expand the indication for its meningococcal conjugate vaccine, Menactra (Meningococcal [Groups A, C, Y and W-135] Polysaccharide Diphtheria Toxoid Conjugate Vaccine), to include a two-dose schedule for infants and children 9 months through 23 months of age.
A new tool is now available to assist in controlling pertussis: the tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap).

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