diphenylhydantoin


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Related to diphenylhydantoin: diphenhydramine, phenytoin

phenytoin

 [fen´ĭ-toin″]
an anticonvulsant used in the treatment of epilepsy other than the petit mal type, the treatment of status epilepticus, and the prevention and treatment of seizures associated with neurosurgery; administered orally. Called also diphenylhydantoin.

phen·y·to·in

(fen'i-tō-in),
An anticonvulsant used in the treatment of generalized tonic clonic and complex partial epilepsy.
Synonym(s): 5, 5-diphenylhydantoin

diphenylhydantoin

(dī-fĕn′əl-hī-dăn′tō-ĭn, -fē′nəl-)
n.

diphenylhydantoin

See phenytoin.

diphenylhydantoin

Alternative pharmacology
A therapeutic drug which some fringe practitioners believe may be used to reverse age-associated mental impairment. Other uses of diphenylhydantoin have included improving concentration, which is attributed to the agent’s ability to stabilise electrical activity of neurons, and strengthening long-term memory.

diphenylhydantoin

References in periodicals archive ?
However, bradycardia, heart block, and hypotension are potential risks related to the use of diphenylhydantoin, as well as valproateinduced hepatotoxicity.
Diphenylhydantoin 25 mg/kg, (100% anticonvulsant on electroshock-induced seizures) was ineffective on inhibiting nantenine-induced seizures.
Ophthalmoplegia resulting from diphenylhydantoin and primidone intoxication.
Diphenylhydantoin fatal hepatic necrosis: a review of literature and report of a case treated exchange transfusion.
Studies comparing tumors observed at the same sites after early postnatal and chronic adult exposures in a single protocol were available for six chemicals that do not act through a mutagenic mode of action [amitrole, dichlorodiphenyltrichloroethane (DDT), dieldrin, ethylene thiourea (ETU), diphenylhydantoin (DPH), polybrominated biphenyls (PBB); Table 5].
Diphenylhydantoin metabolism, blood levels and toxicity.
The role of inflammation in the pathogenesis of gingival enlargement during the administration of diphenylhydantoin sodium to cats.
Possibility of teratogenic exposure with diazepam (9), diphenylhydantoin (3), genetic factors such as trisomy 18 (7), single gene defects in blastogenesis and mutations in homeobox genes such as HLXB9 (3) have been suggested.
a) The chemicals classified as mutagenic were benzidine, benzo(a)pyrene, DEN, safrole, and vinyl chloride; the chemicals classified as not mutagenic were amitrole, diphenylhydantoin, ethylene thiourea, and polybrominated biphenyls.
In utero exposure to the anticonvulsant diphenylhydantoin has been associated with a broad spectrum of abnormalities, including orofacial clefts, nail and digital hypoplasia, growth abnormalities, and mental deficiency (Fedrick 1973; Monson et al.
A method for shifting from oral to intramuscular diphenylhydantoin administration.