Aliquots of stock solutions were transferred to 10 mL volumetric flasks separately to prepare seven standard solutions in concentration ranges 20-140, 32-128, 18-126, 22-154 and 35-107 ug mL-1 for promethazine, diphenhydramine
, desloratadine, levocetirizine and loratadine respectively.
Linearity was determined by preparing dilution of standard solution of diphenhydramine
. Series of 15 solutions were obtained, which contained, respectively, 15.00, 9.00, 5.40, 3.25, 1.95, 1.15, 0.70, 0.40, 0.25, 0.15, 0.10, 0.05, 0.03, 0.02, and 0.01 mg of diphenhydramine
in 5 mL of solution.
, a first-generation antihistamine, can be abused for its effects on the CNS, such as disturbed coordination, irritability, paresthesia, blurred vision, and depression.
As described by Tobian, King, and Ness (2007), the practice of premedicating clients with acetaminophen and diphenhydramine
prior to transfusion originated in the 1950s when several studies concluded that administration of these agents decreased the rate of allergic transfusion reactions (ATRs) and febrile non-hemolytic transfusion reactions (FNHTRs), two classes of transfusion reactions.
is sedating, so ibuprofen PM is probably helping you get to sleep.
Pathologist Dr Mark Egan gave the cause of death as drowning and methadone and diphenhydramine
The company said the active ingredients in this OTC drug are diphenhydramine
hydrochloride (2%) and zinc acetate (0.1%).
An [H.sup.1] receptor antagonist (e.g.' diphenhydramine
) is usually ordered' although an [H.sup.2] (i.e.' cimetidine) may also be indicat ed.
In December, Scheurer and his colleagues reported finding a link between a higher risk for one type of glioma and use of antihistamine drugs such as diphenhydramine
, Benadryl's active ingredient.
One hundred thirty-nine children (aged 2-5 years) with coughing due to an upper respiratory tract infection were randomly assigned to receive a single dose of 2.5 ml of honey, 7.5 mg of dextromethorphan, 6.25 mg of diphenhydramine
, or no treatment.
The child died as a result of "acute diphenhydramine
intoxication," authorities said.
The inquest was told that a post-mortem had revealed an overdose level of the antihistamine drug diphenhydramine
, which is also found in the sleeping medication Nytol.