diphenhydramine


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diphenhydramine

 [di″fen-hi´drah-mēn]
an antihistamine with anticholinergic effects; the hydrochloride salt is used for relief of allergic symptoms, for treatment of anaphylaxis, parkinsonism, and motion sickness or other causes of nausea, vomiting, or vertigo, and as an antitussive; administered orally, intramuscularly, or intravenously. The hydrochloride and citrate salts are used as sedatives and hypnotics and as ingredients in cough and cold preparations; administered orally.

diphenhydramine

(dī′fĕn-hī′drə-mēn′, -mĭn)
n.
A sedating antihistamine drug, C17H21NO, used usually in the form of its hydrochloride to treat symptoms of colds and allergic conditions, motion sickness, insomnia, and parkinsonism.

Benadryl

A proprietary antihistamine developed in the mid-1940s which, like other older sedating agents, has been associated with fatal RTAs/MVAs.
 
Adverse effects Drowsiness, heartburn, dizziness.

diphenhydramine

Diphenadril An anticholinergic and sedative antihistamine. See Imipramine.

diphenhydramine

An ANTIHISTAMINE drug with useful sedative and anti-itching properties. It is a constituent in many over-the counter cough and decongestant remedies with brand names such as Benylin Chesty Cough, Benylin Children's Night Coughs, Benylin with Codeine, Benylin Cough and Congestion, Benylin Dry Cough, Boots Night Time Cough Syrup, Benylin Expectorant, Contac 400, Conovia Night Time Formula, Nirolex for Night Time Coughs, Nytol and so on.
References in periodicals archive ?
Aliquots of stock solutions were transferred to 10 mL volumetric flasks separately to prepare seven standard solutions in concentration ranges 20-140, 32-128, 18-126, 22-154 and 35-107 ug mL-1 for promethazine, diphenhydramine, desloratadine, levocetirizine and loratadine respectively.
Linearity was determined by preparing dilution of standard solution of diphenhydramine. Series of 15 solutions were obtained, which contained, respectively, 15.00, 9.00, 5.40, 3.25, 1.95, 1.15, 0.70, 0.40, 0.25, 0.15, 0.10, 0.05, 0.03, 0.02, and 0.01 mg of diphenhydramine in 5 mL of solution.
Diphenhydramine, a first-generation antihistamine, can be abused for its effects on the CNS, such as disturbed coordination, irritability, paresthesia, blurred vision, and depression.
As described by Tobian, King, and Ness (2007), the practice of premedicating clients with acetaminophen and diphenhydramine prior to transfusion originated in the 1950s when several studies concluded that administration of these agents decreased the rate of allergic transfusion reactions (ATRs) and febrile non-hemolytic transfusion reactions (FNHTRs), two classes of transfusion reactions.
Diphenhydramine is sedating, so ibuprofen PM is probably helping you get to sleep.
Pathologist Dr Mark Egan gave the cause of death as drowning and methadone and diphenhydramine toxicity.
The company said the active ingredients in this OTC drug are diphenhydramine hydrochloride (2%) and zinc acetate (0.1%).
An [H.sup.1] receptor antagonist (e.g.' diphenhydramine) is usually ordered' although an [H.sup.2] (i.e.' cimetidine) may also be indicat ed.
In December, Scheurer and his colleagues reported finding a link between a higher risk for one type of glioma and use of antihistamine drugs such as diphenhydramine, Benadryl's active ingredient.
One hundred thirty-nine children (aged 2-5 years) with coughing due to an upper respiratory tract infection were randomly assigned to receive a single dose of 2.5 ml of honey, 7.5 mg of dextromethorphan, 6.25 mg of diphenhydramine, or no treatment.
The child died as a result of "acute diphenhydramine intoxication," authorities said.
The inquest was told that a post-mortem had revealed an overdose level of the antihistamine drug diphenhydramine, which is also found in the sleeping medication Nytol.