Dipeptidyl-peptidase 4 | definition of dipeptidyl-peptidase 4 by Medical dictionary
DPP4 (redirected from dipeptidyl-peptidase 4)
DPP4 A gene on chromosome 2q24.3 that encodes dipeptidyl-peptidase 4, a ubiquitous, membrane-bound enzyme with roles in nutrition, metabolism, the endocrine system, immune regulation (for instance, it is essential for T-cell receptor (TCR)-mediated T-cell activation), bone marrow mobilisation, apoptosis, cell adhesion and tumourigenesis.
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References in periodicals archive
Long-term dipeptidyl-peptidase 4
inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis.
Hausding et al., "Glucose-independent improvement of vascular dysfunction in experimental sepsis by dipeptidyl-peptidase 4
inhibition," Cardiovascular Research, vol.
Deiuliis et al., "Long-term dipeptidyl-peptidase 4
inhibition reduces atherosclerosis and inflammation via effects on monocyte recruitment and chemotaxis," Circulation, vol.