The role of Tet3 DNA dioxygenase
in epigenetic reprogramming by oocytes.
Prohexadione-calcium (Pro-Ca), originally developed as a plant growth retardant, has recently been used as a 2-oxoglutaric acid-dependent dioxygenase
11) is a cytosolic haem dioxygenase
that catalyzes the oxidative cleavage of the C2-C3 bond of the indole ring of L-Tryptophan.
Ectopic expression of a tomato 9-cis-epoxycarotenoid dioxygenase
gene causes overproduction of abscisic acid.
L'Mellor, "Targeting the immunoregulatory indoleamine 2,3 dioxygenase
pathway in immunotherapy," Immunotherapy, vol.
Functionally, they are a family of dioxygenases
(TET 1/2/3), which convert 5-methylcytosine to 5-hydroxymethyl-cytosine.
The basic defect in alkaptonuria is deficient homogentisate 1, 2 dioxygenase
Tet methylcytosine dioxygenase
2 (TET2), a gene frequently mutated in myeloid disorders, plays a key role in DNA methylation, a critical process in gene expression and cell differentiation.
The new study shows that indolcominc 2,3 dioxygenase
, or IDO, widely known to dampen the immune response and create tolerance, plays an important role in regulating inflammation in that scenario.
The monooxygenase attacks methyl or ethyl substituents of the aromatic ring but dioxygenase
attacks aromatic ring with the formation of 2-hydroxy-substituted compounds.
The phytotoxic lichen metabolite, usnic acid, is a potent inhibitor of plant p- hydroxyphenylpyruvate dioxygenase
NTBC is a potent inhibitor of 4-hydroxyphenylpyruvate dioxygenase
, and thus reduces tyrosine degradation and production of succinylacetone.