Nitisinone (2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione) is a herbicide and potent competitive inhibitor of 4-hydroxyphenylpyruvate dioxygenase
, which is the enzyme that produces HGA.
Also, the application of specific primers for cat1,2 and cat 2,3 genes encoding for production of catechol 1,2 dioxygenase
and catechol 2,3 dioxygenase
enzymes respectively, resulted in amplification of 203 base pair of cat2,3 gene and 605 bp product of cat1,2.
(14.) Lindstedt S, Holme E, Lock EA, Hjalmarson O, Strandvik B.Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase
. Lancet 1992;340:813-7.
BBH, [gamma]-butyrobetaine hydroxylase; TMDL, trimethyllysine dioxygenase
. * P < 0.05 compared with control.
The role of Tet3 DNA dioxygenase
in epigenetic reprogramming by oocytes.
Dendritic cells, indoleamine 2,3 dioxygenase
and acquired immune privilege.
Among the 2-oxoglutaric acid-dependent dioxygenase
genes involved in the pathway, flavanone 3-hydroxylase gene (F3H) and anthocyanidin synthase gene (ANS) had the highest levels of expression, suggesting that the loss of red color might be the reason of the synergistic inhibitory effect of these enzymes especially F3H and ANS in response to Pro-Ca.
The presence of an aromatic dioxygenase
was confirmed by incubation with indole and production of indigo.
," Immunology and Cell Biology, vol.
Cytokines reduce tryptophan availability by activating the enzyme which metabolizes it, indoleamine 2,3- dioxygenase
. Such an excessive indoleamine 2, 3- dioxygenase
stimulation can lead to a tryptophan decrease in serum, which is accompanied by a significant reduction of 5-HT synthesis.
Characterization of the 9-cisepoxycarotenoid dioxygenase
gene family and the regulation of abscisic acid biosynthesis in avocado.