diosgenin


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di·os·gen·in

(dī-os'jen-in),
A steroid sapogenin found in the roots of plants such as the yam; its steroid portion serves as a source from which pregnenolone and progesterone can be prepared.
Synonym(s): nitogenin

diosgenin

Herbal medicine
A steroid saponin closely related to human sex hormones, corticosteroids, vitamin D and cardiac glycosides, which is present in wild yam (Dioscorea species) and Beth root (Trillium erectum). Diosgenin is used for the commercial synthesis of cortisone, pregnenolone, progesterone and other steroids.
References in periodicals archive ?
The steroid diosgenin extracted from the plant is a crucial element in the production of hormones which contributes to the maturity process of the fish.
Diosgenin was extracted and purified as reported previously.
Steroidal sapogenins such as diosgenin, obtainable by hydrolysis of their corresponding saponin molecules, are used by the pharmaceutical industry as raw materials for the synthesis of oral contraceptives and other classes of steroid drugs (Hardman, 1987).
The plant contains saponins; these are glycosides, such as diosgenin, dioscin and dioscorin, and are used in the manufacture of steroids.
Jemiola-Rzeminaska et al., "Structural effects of the Solanum steroids solasodine, diosgenin and solanine on human erythrocytes and molecular models of eukaryotic membranes," Biochimica et Biophysica Acta (BBA)--Biomembranes, vol.
He, "Interaction between ganglioside GM1 and diosgenin in langmuir monolayers at the air/water interface," Scanning, vol.
Lau, "Structure characterization of haemostatic diosgenin glycosides from Paris polyphylia " Phytochemistry, vol.
In the previous study, authors of the present report established a mixed microscopic method for differentiating DN from several Dioscorea species in order to ensure the authentic origin of DN during herb collection [4] and later demonstrated that major constituents of DN include Dioscorea saponins but contained no free diosgenin [5,6] and that DN mediates a cardioprotective effect [7].
Ali et al., "Characterization of in vitro ADME properties of diosgenin and dioscin from Dioscorea villosa" Planta Medica, vol.
Balamurugan, "Diosgenin attenuates vascular calcification in chronic renal failure rats," Molecular and Cellular Biochemistry, vol.