The cows and heifers were synchronized using Ovsynch treatment (Pursley et al., 1995) in which injection of 100 mg of GnRH analogue (Dermarelin; lecirelin acetate 25 mcg/ml, FATRO S.p.A.-pharmaceutical veterinary Industry, Italy) was administered on day 0, 25 mg of PGF2[alpha] (LutalyseTM, Dinoprost
tromethamine 5 mg/ml, Pfizer manufacturing Belgium NV-Puurs-Belgium) on day 7 and 2nd injection of GnRH on day 9 (Figure 1).
Estrus synchronization was achieved by administration of prostaglandin (PC) [F.sub.2a] (25 mg dinoprost
, Lutalyse, Zoetis, Louvain-la-Neuve, Belgium) or by Ovsynch .
Some projects like alprostadil-alfadex or dinoprost
made use of existing technologies and represented only an extension of current technological procedures.
The cows in Group-I and II were treated intramuscularly with 5 mg Methyl ergometrine maleate (Nexbolic (a)) and 25 mg of Dinoprost
tromethamine, a natural PG[F.sub.2[alpha] (Lutalyse (b)) respectively, immediately after parturition.
At the fifth day after the implants were inserted, animals from CIDR and MAP groups were injected with 12.5mg dinoprost
5ml prostaglandin F2 alpha containing 25mg dinoprost
administered 11 days apart.
Unoprostone, used as the isopropyl ester for the treatment of glaucoma and ocular hypertension, is like latanoprost, a synthetic analogue of dinoprost
. Misoprostol a synthetic PGE1 analogue, has been marketed by the name of Cytotec by Searle, Arthrotec by Pfizer, and Prozotec by Atco, STmom by Zafa .
El grupo T1 (13 becerras) fue tratado el dia 0 con una inyeccion intramuscular de [PGF.sub.2] [alfa] (Cloprostenol 530 mcg/2 ml) y al grupo T2 (16 becerras) se les administro el dia 0 una inyeccion intravulvar de [PGF.sub.2] [alfa] (Dinoprost