Dinitrochlorobenzene | definition of dinitrochlorobenzene by Medical dictionary
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a substance applied topically as a test for delayed hypersensitivity reactions. The compound has also been used as an immunotherapeutic agent to treat skin tumors.
a hapten whose application to the skin results in a contact hypersensitivity; abbreviated DNCB. Sometimes used to test for type IV or delayed type hypersensitivity reactions.
References in periodicals archive
Sensitizing and challenging dose of Dinitrochlorobenzene
(DNCB) was applied at the marked places at right and left sides on 2nd and 8th days respectively with the help of tuberculin syringe.
In a study done by Sajid et al 2007, on rabbits, the cell mediated immunity against dinitrochlorobenzene
(DNCB) was determined by delayed-type hypersensitivity.
Allergic rhinitis induced by intranasal sensitization and challenge with trimellitic anhydride but not with dinitrochlorobenzene
or oxazolone in A/J mice.