Clinico-hematologic and biochemical profile of dimorphic anemia
with bone marrow study.
In this study, cases of microcytic hypochromic anemia are highest, i.e., 2410 (50.47%) which is most common in this area and the next common anemia is normochromic nonnocytic anemia (2260 [47.32%]) followed by dimorphic anemia
, i.e., 314 (6.57%), hemolytic anemia, i.e., 193 (4.04%), macrocytic anemia, i.e., 188 (3.93%), pancytopenia, i.e., 51 (1.06%), and sickle cell anemia, i.e., 38 (0.79%) (Table 5).
Graph 1 < 1 yr 1.5 Yr 6.12 Yr 13.18 Yr 9% 16% 30% 45% Microcytic hypochromic anemia 33.3 43.7 33.3 20 Macrocytic anemia 11.11 6.3 18.3 18.3 Dimorphic anemia
1.1 12.5 40 53.3 Haemolytic anemia 44 31.2 6.7 2.2 Normocytic normochromic anemia 0 6.3 6.7 11.1 Note: Table made from bar graph.
A histogram distribution that is bimodal can be seen in various situations, such as dimorphic anemia
, cold agglutinin disease, after the transfusion of normal erythrocytes into a person with abnormally sized erythrocytes, in the presence of erythrocyte fragments, or with agglutination.
Anisopoikilocytosis was the predominant finding in megaloblastic anemia (MA), dimorphic anemia
(DA), iron deficiency anemia (IDA) and erythroid hyperplasia (EH).
Peripheral smear showed dimorphic anemia
followed by macrocytic anemia in majority of cases.
The most common type was dimorphic anemia
in 28 cases and in 1 case it was macrocytic anemia showing megaloblastic change in the bone marrow.
was predominant picture (43 %) on peripheral smear.
She had a hemoglobin level of 5 gm/dl, total count of 2390 cells/cumm, peripheral smear revealed dimorphic anemia
of severe degree with leucopenia.
In the present study, normocytic normochromic anemia is the most common type (55%) followed by microcytic hypochromic anemia (27%), normocytic hypochromic anemia (11%), macrocytic anemia (4%) and dimorphic anemia
(3%) in contrast to study done by Kapur et al, where microcytic hypochromic anemia was the commonest type (43.2%) followed by normocytic normochromic anemia (27%), normocytic hypochromic anemia (17%), macrocytic anemia (10%) and dimorphic anemia
(2.7%) (Table 2).
The most common cause of pancytopenia among the 155 cases was found to be megaloblastic anemia which was present in 67 (43.22%), with maximum number of cases in 20-40 years age group, male: female ratio was 1.79:1(43:24), the second most common cause of pancytopenia was hypoplastic anemia 20/155 (12.90%) followed by Dimorphic anemia
13/155 (8.38%) with maximum frequency of cases in females both under 14 and 20-40 years age group, male female ratio being 0.81:1 and 0.85:1 respectively.
The commonest type of anemia in the present study was Microcytic Hypochromic anemia (82.5%) followed by Dimorphic anemia