dimethylsulfoxide


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Related to dimethylsulfoxide: Dimethyl sulfate, Dimethyl sulfide

dimethylsulfoxide

(dī-mĕth′əl-sŭl-fŏk′sīd′)
n.
DMSO.

DMSO

Alternative medicine
A substance that occurs naturally in minute amounts in certain foods, which has industrial and health-related applications. Animal studies have shown it to have analgesic, anti-inflammatory, antimicrobial, vasodilatory and other properties; up to the 1960s, DMSO had been administered orally, topically or parenterally by mainstream physicians for various conditions, including arthritis, bursitis, cancer, emphysema, mental illness and pain. In the face of its association with lenticular degeneration, DMSO was removed from general use; some practitioners of alternative healthcare continue to recommend DMSO for these and other uses.
 
Toxicity
Topical DMSO is associated burning, itching and an unpleasant odour.
 
Mainstream medicine
DMSO is FDA-approved for treating interstitial cystitis, and may be of use in treating scleroderma, sprains, arthritis, cerebrovascular accidents, familial amyloidotic polyneuropathy and acetaminophen hepatotoxicity. DMSO reduces the ice crystals formed in frozen section tissues from the operating suite, and may be an effective cryopreservative.
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References in periodicals archive ?
Note: DBT, dibutyltin; DMSO, dimethylsulfoxide; SEM, standard error of the mean; TBT, tributyltin.
In the present study, data on density, viscosity, refractive index, and speed of sound of binary mixtures of dimethylsulfoxide (DMSO) + 1-phenylethanone (acetophenone) and 1,4-Dimethylbenzene (para-xylene) at 313.15, 318.15, 323.15, and 328.15 K has been measured experimentally.
The precipitate was vacuum dried obtaining a yellow powder which was soluble in dimethylsulfoxide (DMSO).
Graham, "Dimethylsulfoxide (DMSO) treatment reduces infarction volume after permanent focal cerebral ischemia in rats," Neuroscience Letters, vol.
(2,5,7-10,13-15) Antimicrobial and anti-inflammatory products (eg, dimethylsulfoxide, hemorrhoid cream, triple antibiotic ointment, silver sulfadiazine cream) as well as hypertonic footbaths (eg, hypertonic saline solution, magnesium sulfate) provide local control of infection and inflammation.
RPMI-1640 medium, fetal bovine serum (FBS), penicillin, and streptomycin were purchased from Sigma (Germany), dimethylsulfoxide (DMSO) and trypan blue from Merck (Germany), trypsin/EDTA solution from Gibco (U.K), and 3-(4,5-dimetylthiazol-2-YL)-2,5-diphenyltetrazolium bromide (MTT reagent), Cell Death Detection ELISA plus kit, and In Situ Cell Death Detection Kit, POD from Roche Diagnostics GmbH (Germany) and DAB (3, 3'-diaminobenzidine).
RCH[Cl.sub.3] and RBuOH samples were re-suspended in 50% dimethylsulfoxide (DMSO50), and all RH[2.sub.O] samples were diluted with Milli-Q distilled water (Millipore[R], Bedford, USA), to a concentration of 200 mg/mL for testing.
(a) XPNPEP2 Clinical Genotype (c) Setting 1 C/ Allergic reaction; vascular surgery 2 C/C TACO; anemia and CHF 3 C/ DMSO toxicity; AML 4 C/C(C/) Nonhypotensive reaction Abbreviations: AML, acute myelogenous leukemia; CHF, congestive heart failure; DMSO, dimethylsulfoxide; FFP, fresh-frozen plasma; NK, not known (because of deidentification of data prior to analysis); PBSC, peripheral blood stem cells; RBC, red blood cells; TACO, transfusion-associated circulatory overload.
The plates were destained for approximately 10 min with an aqueous solution of 10% acetic acid and 2% dimethylsulfoxide.21
1) like CH3CN (MeCN), CHCl3 (CF), CH2Cl2 (DCM), CH3OH (MeOH), dimethylformamide (DMF) and dimethylsulfoxide (DMSO) at 2.8x10-5 M.
Samples were dissolved in dimethylsulfoxide (DMSO) and diluted with artificial sea salt water so that final DMSO concentration did not exceed 0.05%.