dimethylnitrosamine


Also found in: Dictionary, Acronyms, Wikipedia.
Related to dimethylnitrosamine: quinoline

dimethylnitrosamine

(dī-mĕth′əl-nī-trō′sə-mēn′, -nī′trō-săm′ĭn)
n.
See NDMA.
Mentioned in ?
References in periodicals archive ?
Orlandi, "A morphological study of the early stages ofhepatic fibrosis induced by low doses of dimethylnitrosamine in the rat," Journal of Hepatology, vol.
Liu et al., "Role of hepatic sinusoidal endothelium injury in hepatic fibrogenesis induced by dimethylnitrosamine in rats," Zhonghua Gan ZangBingZa Zhi, vol.
Mutagenicity of two potent carcinogens, dimethylnitrosamine and diethylnitrosamine, in Neurospora crassa.
Dimethylnitrosamine: formation of mutagenic compounds by interaction with mouse liver microsomes.
Abbreviations ED: Erectile dysfunction DMN-dI: Dimethylnitrosamine N-demethylase I AHH: Arylhydrocarbon hydroxylase ECOD: 7-Ethoxycoumarin-O-deethylase EROD: Ethoxyresorufin-O-deethylase PDE5Is: Phosphodiesterase-5 inhibitors ROS: Reactive oxygen species CYP: Cytochrome P450.
Argus, "Differential effect of polycyclic hydrocarbons on the demethylation of the carcinogen dimethylnitrosamine by rat tissues," Life Sciences, vol.
Effect of age at treatment on incidence and type of renal neoplasm induced in the rat by a single dose of dimethylnitrosamine. Cancer Res 39:4965-4970.
Based on the alkaline elution method, the plant extract prevented in vivo DNA single-strand breaks caused by dimethylnitrosamine (DMN) in hamster liver cells.
(10) reported that cultured human esophageal cells activated dimethylnitrosamine into DNA-binding metabolites.
For example, it is currently unclear whether any of the proposed alternatives should be required to predict the carcinogenicity of presumed nongenotoxic rodent carcinogens such as sodium saccharin and limonene, or whether their value should be judged in relation to their sensitivity to genotoxic (mutagenic) carcinogens such as dimethylnitrosamine, benzo[a]pyrene, and aflatoxin [B.sub.1].
Blastomogenic activity of dimethylnitrosamine in animals of different age.