cacodylic acid

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Related to dimethylarsinic acid: Cacodylic acid

cac·o·dyl·ic ac·id

(kak'ō-dil'ik as'id),
Arsenical contact herbicide that defoliates or desiccates a wide variety of plant species.

cacodylic acid

/cac·o·dyl·ic ac·id/ (kak″o-dil´ik) dimethyl arsinic acid, a highly toxic herbicide.

Agent Blue

An arsenic-based herbicide used to destroy broadleaf plants and trees (grass, rice, bamboo, bananas, etc.), especially rice paddies during the Vietnam War. During the war, 1.25 million US gallons of Agent Blue were used, successfully destroying 500,000 acres of crops.

cacodylic acid

pharmaceutical aliphatic organic arsenical; see also organic arsenical.
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Oral exposure of dimethylarsinic acid, a main metabolite of inorganic arsenics, in mice leads to an increase in 8-Oxo-2'-deoxyguanosine level, specifically in the target organs for arsenic carcinogenesis.
Chromatographic separation and identification of products from the reaction of dimethylarsinic acid with hydrogen sulfide.
Laboratory Procedure Manual: Arsenobetaine, Arsenocholine, Trimethylarsine Oxide, Monomethylarsonic Acid, Dimethylarsinic Acid, Arsenous (III) Acid, Arsenic (V) Acid, Total Arsenic.
Dimethylarsinic acid causes apoptosis in HL-60 cells via interaction with glutathione.
Arsenic (As) occurs as monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) in humans, and the methylation pattern demonstrates large interindividual differences.
In vitro biotransformation of dimethylarsinic acid and trimethylarsine oxide by anaerobic microflora of mouse cecum analyzed by HPLC-ICP-MS and HPLC-ESI-MS.
Metabolic conversion of inorganic As (iAs) to dimethylarsinic acid (DMA) reduces toxicity and facilitates urinary As (uAs) elimination, but the intermediate metabolite monomethylarsonic (MMA) may have increased cytoxic and genotoxic effects.
Key WORDS: arsenic, Bangladesh, cobalamin, creatinine, dimethylarsinic acid, folate, homocysteine, monomethylarsonic acid, one-carbon metabolism.
METHODS: We used hydride generation-atomic absorption spectrometry (HGAAS) to determine iAs, monomethylarsonic acid (MMA), and dimethylarsinic acid (DMA).
RESULTS: In supermarket-bought rice, arsenic was present entirely in the inorganic form compared to greenhouse-grown rice (using irrigation water contaminated with sodium arsenate), where most (~ 86%) arsenic was present as dimethylarsinic acid (organic arsenic).
Effects of dietary dimethylarsinic acid on the urine and urothelium of rats.
Arsenic is methylated to monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) via one-carbon metabolism, a biochemical pathway that is dependent on folate.