dihydropyrimidine dehydrogenase

(redirected from dihydrouracil dehydrogenase)

di·hy·dro·py·rim·i·dine de·hy·dro·gen·ase

(dī-hī'drō-pī-rim'ĭ-dēn dē-hī'drō-jen-ās'), [MIM*274270]
An enzyme in pyrimidine biosynthesis that reacts 5,6-dihydrouracil with NADP+ to form uracil and NADPH; it also acts on dihydrothymine; a deficiency of this enzyme can result in hyperuracil thyminuria.
References in periodicals archive ?
Dihydrouracil dehydrogenase activity in normal, differentiating and regenerating liver and in hepatomas.

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