dihydrotestosterone


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dihydrotestosterone

 (DHT) [di-hi″dro-tes-tos´tĕ-rōn]
an androgenic hormone formed in peripheral tissue from testosterone; thought to be the androgen responsible for development of the male primary sex characters during embryogenesis and of male secondary sex characters at puberty, and for adult male sexual function.

dihydrotestosterone

/di·hy·dro·tes·tos·te·rone/ (DHT) (-tes-tos´tĕ-rōn) an androgenic hormone formed in peripheral tissue by the action of 5 on testosterone; thought to be the androgen responsible for development of male primary sex characters during embryogenesis and of male secondary sex characters at puberty, and for adult male sexual function.

dihydrotestosterone

(dī-hī′drō-tĕs-tŏs′tə-rōn′)
n. Abbr. DHT
An androgen that is produced from testosterone in the body and is important in the formation of the male reproductive organs and in the development of male secondary sex characteristics.

dihydrotestosterone (DHT)

[di-hi′drōtestos′terōn]
an androgenic hormone formed in peripheral tissue from testosterone. It is thought to be the androgen responsible for development of the male primary sex characters during embryogenesis and of male secondary sex characters at puberty and for adult male sexual function.

dihydrotestosterone

Dehydrotestosterone Physiology A potent C19 androgen produced from testosterone, which is the predominant androgen in skin, prostate, seminal vesicles, epididymis ↑ in Hirsutism, polycystic ovary syndrome, ↑ 5-alpha reductase activity ↓ in Hypogonadism, ↓ 5-alpha reductase activity due to drug interactions

dihydrotestosterone

reduced, more active form of testosterone in males; associated with follicular atresia in the female.
References in periodicals archive ?
Also dihydrotestosterone levels increased significantly only in group receiving maximum dosage (Table 1).
Dihydrotestosterone (DHT) and flutamide were purchased from Fluka and Sigma (Taufkirchen, Germany), respectively.
Gay and bisexual men have higher levels of free testosterone in their bodies, which easily converts to dihydrotestosterone, a hormone that is associated with the male aging process," Kryger said of the phenomenon.
The class of drugs inhibits the 5-alpha reductase enzyme, significantly lowering the level of the primary male hormone in the prostate, dihydrotestosterone (DHT), without affecting testosterone levels elsewhere in the body.
This converts the male hormone testosterone into dihydrotestosterone (DHT) which has a harmful effect on the follicles, causing them to shrink.
Another drug, finasteride (Proscar), interferes with the conversion of testosterone to dihydrotestosterone, a hormone that stimulates the prostate to grow.
Finasteride blocks 5[alpha]-reductase, an enzyme that converts testosterone to the more potent dihydrotestosterone, and may therefore help prevent prostate cancer.
Finasteride, an inhibitor of 5a-reductase, inhibits the conversion of testosterone to dihydrotestosterone, the primary androgen in the prostate, and may reduce the risk of prostate cancer.
The drug achieves both effects by ratcheting down production of dihydrotestosterone, a hormone linked to male pattern baldness and enlargement of the prostate.
This was the case with finasteride, a drug that prevents the production of a male hormone called dihydrotestosterone (DHT).
Sexually undifferentiated larval tiger salamanders (Ambystoma tigrinum), with immature gonads were immersed in a sub lethal solution of technical-grade TCDD and injected with dihydrotestosterone (DHT) or estradiol ([E.
The mechanism of action of finasteride is to inhibit the steroid 5-alpha reductase, which is an intracellular enzyme that converts testosterone into the potent androgen 5-alpha dihydrotestosterone (DHT).

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