dihydrotachysterol


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Related to dihydrotachysterol: ergocalciferol

dihydrotachysterol

 [di-hi″dro-tah-kis´ter-ol]
an analogue of ergosterol, used as a calcium regulator in the management of hypocalcemia in conditions such as rickets, osteodystrophy, hypoparathyroidism, hypocalcemic tetany, and complications of renal dialysis; administered orally.

ta·chys·ter·ol

(tă-kis'tĕr-ōl),
Sterol(s) formed by ultraviolet irradiation of any 5,7-diene-3β-sterol, which breaks the 9,10 bond, but usually from either or both of ergosterol and lumisterol to produce tachysterol2 (ertacalciol, (6E,22E)-9,10-secoergosta-5(10),6,8,22-tetraen-3β-ol) and from 7-dehydrocholesterol to produce tachysterol3 (tacalciol, (6E,3S)-9,10-secocholesta-5(10),6,8-trien-3β-ol). When reduced to the 5,7-diene (or 5,7,22-triene) form, dihydrotachysterol3 (10,19-dihydrocalciol) or dihydrotachysterol2 (10,19-dihydroercalciol), antirachitic action appears. This property has been of therapeutic interest, but tachysterol is being replaced by the true vitamin D hormone (calcitriol) and its derivatives.

dihydrotachysterol

(dī-hī′drō-tə-kĭs′tə-rôl′, -rōl′)
n. Abbr. DHT
A rapidly acting form of vitamin D, C28H45OH, prescribed in the treatment of hypocalcemia.

dihydrotachysterol

A vitamin D analogue drug used to treat low blood calcium. A brand name is A.T. 10.
References in periodicals archive ?
Dihydrotachysterol intoxication treated with pamidronate: a case report.

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