dihydrosphingosine

dihydrosphingosine

(di-hi?dro-sfing'go-sen)
CH3-[CH2]14-CHOH-CH(NH2)-CH2OH; a long-chain amino alcohol present in sphingolipids, also known as sphinganine.
See: sphingolipid; sphingosine
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References in periodicals archive ?
These antimicrobials are the long-chain bases--sphingosine, dihydrosphingosine, and possibly 6-hydroxysphingosine.
Sphingosine and dihydrosphingosine always occurred together, so no separate designation was proposed for dihydrosphingosine.
Again, sphingosine was always accompanied by dihydrosphingosine as indicated by S/DS.
The compounds, sphingosine and dihydrosphingosine, were found to be at significantly lower concentrations in blood samples from multiple sclerosis patients.
The report states: "Sphingosine and dihydrosphingosine have been previously found to be at lower concentrations in the brain tissue of patients with multiple sclerosis.
Pei et al., "Dihydrosphingosine 1-phosphate stimulates MMP1 gene expression via activation of ERK1/2-Ets1 pathway in human fibroblasts," The FASEB Journal, vol.
Only the conversions of dihydrosphingosine and not of other sphingosine species such as phytosphingosine are shown.
Abbreviations: AST, aspartate aminotransferase; Cer, ceramide; Cer-1P, phosphoceramide; CK, ceating kinase; dhCer, dihydroceramide; dhCer-1P, phosphodihydroceramide; dhSph, dihydrosphingosine; DC, diglyceride; FA, fatty acid; GBE, Ginkgo biloba L.
San Feliciano, "New antinociceptive agents related to dihydrosphingosine," Pharmacological Reports, vol.
Enzymatic synthesis of 1-phosphate esters of 4t-sphingenine (sphingosine), sphinganine (dihydrosphingosine), 4-hydroxysphinganine (phytosphingosine) and 3dehydrosphinganine by erythrocytes," Hoppe-Seylers Zeitschrift Fur Physiologische Chemie, vol.
The SPL gene was first identified in budding yeast and named DPL1 (for dihydrosphingosine phosphate lyase, one of the natural substrates formed in yeast cells) [49].
Among various organisms, several metabolic divergences appear after the formation of sphinganine (dihydrosphingosine).

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