diffuse panbronchiolitis


Also found in: Acronyms.

pan·bron·chi·o·li·tis

(pan'bron-kē-ō-lī'tis),
Idiopathic inflammation and obstruction of bronchioles, eventually accompanied by bronchiectasis; cases originally reported are almost all from Japan.
Farlex Partner Medical Dictionary © Farlex 2012

diffuse panbronchiolitis

A severe idiopathic inflammatory condition that diffusely involves the bronchioles. It is most common in eastern Asian males and, if untreated, leads to bronchiectasis. Macrolide antibiotics—e.g., erythromycin—slows but does not halt or reverse disease progression.
 
Clinical findings
Chronic sinusitis, wheezing, crackles, dyspnoea, purulent sputum, hypoxia, hypercapnia, pulmonary hypertension, cor pulmonale and eventually respiratory failure.
 
Prognosis
Without erythromycin, 10-year survival is 33%; with it, 90%.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Diffuse panbronchiolitis observed in an Italian male.
Diffuse panbronchiolitis in a Hispanic man with travel history to Japan.
A report of the first three cases of diffuse panbronchiolitis in Malaysia.
Diffuse panbronchiolitis: histologic diagnosis in unsuspected cases involving North American residents of Asian descent.
Diffuse panbronchiolitis: case report and review of the literature.
Diffuse panbronchiolitis, the first case reports in Thailand.
A case of diffuse panbronchiolitis. Aust N Z J Med.
Diffuse panbronchiolitis observed in a white man in Turkey.
Diffuse panbronchiolitis: role of macrolides in therapy.
Diffuse panbronchiolitis: a treatable sinobronchial disease in need of recognition in the United States.
Diffuse panbronchiolitis: an underdiagnosed disease?: study of 4 cases in Brazil.
Diffuse panbronchiolitis. Semin Respir Crit Care Med.

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