mesangial proliferative glomerulonephritis

(redirected from diffuse mesangial proliferation)

mes·an·gi·al pro·lif·er·a·tive glo·mer·u·lo·ne·phri·tis

glomerulonephritis characterized clinically by nephrotic syndrome and histologically by diffuse glomerular increases in endocapillary and mesangial cells and in mesangial matrix; in some cases, there are mesangial deposits of IgM and complement.
Farlex Partner Medical Dictionary © Farlex 2012

mes·an·gi·al pro·lif·er·a·tive glo·mer·u·lo·ne·phri·tis

(mes-an'jē-ăl prō-lif'ĕr-ă-tiv glō-mer'yū-lō-nĕ-frī'tis)
Disorder characterized clinically by the nephrotic syndrome and histologically by diffuse glomerular increases in endocapillary and mesangial cells and in mesangial matrix; in some cases, there are mesangial deposits of IgM and complement.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
CLASS III###IIIb: Diffuse Mesangial Proliferation with
CLASS IV###IVb: Diffuse Mesangial Proliferation with
The histopathological diagnoses of 6 steroid-resistant patients who underwent biopsy included FSGS (n=3), C1q nephropathy (n=1), diffuse mesangial proliferation (n=1) and membraneous nephropathy (n=1).
The results of 3 of 6 patients who had renal histopathology and who achieved full remission with cyclophosphamide were as follows: FSGS, MLD and diffuse mesangial proliferation. Full remission was achieved in 2 of the patients who used cyclosporine (histopathology: FSGS in one and diffuse mesangial proliferation in the other) during the time when they used the drug and partial remission was achieved in three patients (histopathology: FSGS in two and diffuse mesangial proliferation in one patient).
The major finding on light microscopy is focal or more often diffuse mesangial proliferation and matrix expansion.
Grade III: moderate, diffuse mesangial proliferation and increased matrix were observed.
Grade IV: severe, diffuse mesangial proliferation and increased matrix were observed.
The morphologic features at light microscopy may vary from MCD-like to diffuse mesangial proliferation to segmental sclerosis.

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