diffuse cutaneous leishmaniasis

(redirected from diffuse leishmaniasis)

dif·fuse cu·ta·ne·ous leish·man·i·a·sis

leishmaniasis caused by several New and Old World species and strains of Leishmania (L. mexicana amazonensis, L. m. pifanoi, possibly L. m. garnhami and L. m. venezuelensis; in Ethiopia, L. aethiopica, and unidentified leishmanial agents in Namibia and Tanzania). The condition is associated with a suppressed cell-mediated immune response, so that the nonulcerating, nonnecrotizing cutaneous lesions can spread widely over the body; great numbers of parasite-filled macrophages are found in the dermal lesions. Healing does not seem to occur unless an acquired cellular hypersensitivity can develop.
See also: cutaneous leishmaniasis.

dif·fuse cu·ta·ne·ous leish·man·i·a·sis

(di-fyūs' kyū-tā'nē-ŭs lēsh'mă-nī'ă-sis)
A disorder caused by several New and Old World species and strains of Leishmania. The condition is associated with a suppressed cell-mediated immune response.
References in periodicals archive ?
Other diagnoses include cutaneous leishmaniasis, as occurred for 2 of the soldiers, as well as diffuse leishmaniasis, chromomycosis, sporotrichosis, lepromatous or tuberculoid dimorphic leprosy, mycetoma, phaeohyphomycosis, pyoderma, Kaposi sarcoma, sarcoidosis, keloid scars, histiocytosis of Langerhans cells, melanoma, dermatofibrosarcoma, lymphoma, squamous cell carcinoma, and cutaneous metastases (3,17,40,41).
amazonensis is of particular importance because it is one of the most frequent species that causes human disease and specifically causes anergic diffuse leishmaniasis, a disfiguring cutaneous disease that is very difficult to cure [24].
Leishmaniasis have been characterized in HIV-1 infected individuals, who may present multiple cutaneous lesions, resembling the picture of diffuse leishmaniasis more frequently found in immunosuppressed patients (RABELLO et al., 2003).

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