differential gene expression


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dif·fer·en·tial gene ex·pres·sion

gene expression that responds to signals or triggers; a means of gene regulation, for example, effects of certain hormones on protein biosynthesis.

differential gene expression

The biochemical processes that determine which genes are actively transcribed and translated into mRNA and proteins in a cell and under what conditions.
See also: expression
References in periodicals archive ?
Differential gene expression in liver and kidney were measured 24 hr after the last dose using the Agilent rat chip.
The linearity of the Ovation RNA amplification system was evaluated by determination of differential gene expression between total RNA samples, UHR (reference human RNA), and human skeletal muscle (each at 20 ng of total RNA).
PCB153 exposure in this study was associated with differential gene expression of proinflammatory cytokines, including IL1, IL2, and the immune response gene MX1.
Differential gene expression technologies for identifying surrogate markers of drug efficacy and toxicity.
A high-throughput system for acquisition, analysis and 3D display of quantitative data related to depression will provide a platform for preclinical drug development, with broad utility for comprehensive analysis of differential gene expression patterns in the mouse brain.
One of the goals of the NCT is to determine whether phenotypic alterations can be associated with differential gene expression (DGE) changes.
Microarray methods were initially developed to study differential gene expression using complex populations of RNA (1).
Intronn has developed and patented a new technology for gene therapy that exploits the differential gene expression between normal and diseased cells.
D, Director Marketing & Alliances, Gene Logic says, "State-of-the-art technologies like Genotyping, Differential Gene Expression, Genome Wide Association, SNPs et cetera have contributed immensely to global biomarker discovery programs as we all continue our pursuit for improved and affordable therapeutics.
There are several approaches for analyzing the effects of environmental factors in experimental animals, including differential gene expression using cDNA microarrays, RAGE, and SAGE; as well as proteomic methods to determine changes in protein levels and protein modifications.
Differential gene expression data for 42 normal tissues (1,809 specimens) and 172 diseased tissues (2,206 specimens) were analyzed.
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