(b) Venn diagram of differential DNA methylation and
differential gene expression analysis.
Our goal, therefore, is to use flux variability information as a measure of robustness of the system in combination with
differential gene expression information to identify the points of perturbation in the network to ultimately characterize cell responses under chemical perturbations.
Previous studies have shown that the pathogenesis of pulmonary fibrosis is related to various factors, including DE-miRNAs, DEGs, and microRNA-controlled
differential gene expression [30, 31].
Differential gene expression analysis of the VC, VD, and VE groups was performed using the DESeq R package (1.18.0).
Differential gene expression in both mRNAs and miRNAs may play a role in hypertension disparities through modulating oxidative stress.
Keywords: Combined light sources;
Differential gene expression; Extended photoperiod; Growth rate; Oreochromis niloticus
Differential gene expression of many developmental and pathological processes is partly controlled by transcription factors (TFs), proteins that bind to the promoter regions of genes affecting their transcription to mRNA [16].
In this first major synthesis of homology in decades, the author (Ecology and Evolutionary Biology, Yale) develops the concept of character identity networks--regulatory networks of genes that enable
differential gene expression independently of the form of the character being expressed.
Methylation sequencing was applied to luminal and basal/TNBC breast cancer cell lines, revealing differential DNA methylation patterns associated with
differential gene expression patterns of these cancer subtypes.
In this context, the identification and characterization of
differential gene expression may reveal important molecular markers in the events mentioned above.
Differential gene expression between groups was first evaluated by comparing each treatment (axial versus control, shear versus control, and shear versus axial) at each time point.
Simon, "A random variance model for detection of
differential gene expression in small microarray experiments," Bioinformatics, vol.
