differential blood count


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differential blood count

The number and type of white blood cells as determined by microscopic examination of a thin layer of blood on a glass slide stained to show the shape of the various cells. The number and variety of white cells in a sample of a given size are obtained. Even though the red cells are not counted by this method, their shape, size, and color can be evaluated. Some blood diseases and inflammatory conditions may be recognized in this way. In a differential count, the varieties of the leukocytes and their percentages normally should be: neutrophils (segmented), 40% to 60%; eosinophils, 1% to 3%; basophils, 0.5% to 1%; lymphocytes, 20% to 40%; monocytes, 4% to 8%.
See also: count

differential blood count

An assessment of the percentage numbers of the various types of white cells present in the blood-the neutrophil polymorphs (40–75%), lymphocytes (20–45%), monocytes (2–10%), eosinophils (up to 6%) and basophils (up to 1%). Changes in the normal percentages are usually significant.
References in periodicals archive ?
New generations of hematology analyzers produce fast and reliable data on blood count, while at the same time offering screening information on differential blood count. The aim of this study was to evaluate a Cell-Dyn [R] (CD) 1700CS (Abbott Diagnostics, Abbott Park, IL) hematology analyzer that determines 18 parameters, including three-part differential blood count.
Each of 269 samples was classified as truly negative (TN), denoting a differential blood count within the reference range by both methods; truly positive (TP), denoting a differential blood count signalized by the analyzer as pathologic, which was confirmed by manual differentiation; falsely positive (FP), denoting a result signalized by the analyzer as pathologic, whereas on manual differentiation it showed no deviations from a sample of a healthy subject; and falsely negative (FN), denoting a differential blood count result that the analyzer failed to signalize as pathologic, whereas on manual differentiation the sample was found to be pathologic.

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