diethylstilboestrol

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Related to diethylstilboestrol: diethylstilbestrol

diethylstilboestrol

Diethylstilbestrol, DES. A synthetic female sex hormone. This is now restricted in use to the treatment of certain cancers of the PROSTATE and the breast. If given to pregnant women it can cause cancer in the female offspring. See also STILBOESTROL.

References in periodicals archive ?

Moreover, all of the patients had previously failed treatment with LHRH analogs and antiandrogens, while 22 patients (50%) had failed treatment with diethylstilboestrol and 20 patients (45%) had failed treatment with steroids.

Cougar Biotechnology Presents Positive CB7630 Phase II Data at Prostate Cancer Foundation Scientific Retreat

Moreover, all of the patients had previously failed treatment with LHRH analogs and antiandrogens, while 20 patients (53%) had failed treatment with diethylstilboestrol and 19 patients (50%) had failed treatment with steroids.

Cougar Biotechnology Announces Presentation of Positive CB7630 Clinical Data at ESMO Conference

In the trial, CB7630 was administered once daily to chemotherapy-naove patients with castration refractory prostate cancer (CRPC), who had progressive disease despite treatment with LHRH analogues and multiple other hormonal therapies including antiandrogens, diethylstilboestrol and dexamethasone.

Cougar Biotechnology Announces Presentation of Positive Phase I and Phase II Data at ASCO Prostate Cancer Symposium