diethylenetriamine pentaacetic acid


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pentetic acid

 [pen-te´tik]
diethylenetriamine pentaacetic acid, DTPA; a chelating agent (iron) with the general properties of the edetates; used in preparing radiopharmaceuticals.

di·eth·yl·ene·tri·a·mine pen·ta·a·ce·tic ac·id (DTPA),

(dī-eth'il-ēn-trī'ă-mēn pen'tă-ă-sē'tik as'id),
An important chelating agent used in therapy (for example, in therapy for lead poisoning), and in metal-containing diagnostic agents for magnetic resonance imaging and nuclear scanning.

di·eth·yl·ene·tri·a·mine pen·ta·a·ce·tic ac·id

(DTPA) (dī-eth'il-ēn-trī'ă-mēn pen'tă-ă-sē'tik as'id)
An important chelating agent used in therapy and in metal-containing diagnostic agents for magnetic resonance imaging and nuclear scanning.
References in periodicals archive ?
Matsui, T Gabata et al., "Relationship between signal intensity on hepatobiliary phase of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced MR imaging and prognosis of borderline lesions of hepatocellular carcinoma," European Journal of Radiology, vol.
[7] Nonstandard abbreviations: ACTH, adrenocorticotropic hormone; PET, positron emission tomography; CT, computed tomography; [sup.68]Ga-DOTATOC, [sup.68]Ga labeled 1,4,7,10-tetraazacyclododecane-N,N',N",N"'-tetraacetic acid-D- [Phe.sup.1][Tyr.sup.3]-octreotide; SPECT, single-photon emission computed tomography; [sup.111I]nDTPA-octreotide [sup.111]In-labeled diethylenetriamine pentaacetic acid octreotide.
The chelator diethylenetriamine pentaacetic acid is effective in preventing nickel, chrome, and copper dermatitis.
The team added to deodorants a chemical called butylated hydroxytoluene, which releases iron bound in sweat, and diethylenetriamine pentaacetic acid. This agent mops up free iron, keeping it away from microbes.
DTPA (diethylenetriamine pentaacetic acid), sold as Sequestrene 330 and Sprint 330, is useful where soil pH is 7.2 or less and soils are not high in clay.
An axial three-dimensional high-resolution T1-weighted fast gradient echo fat-suppressed sequence (TE/TR 2.4/4.6 ms; inversion delay spectral presaturation attenuated by inversion recovery (SPAIR) 90 ms; flip angle 10; FOV 360x360 [mm.sup.2], acquired voxel size 0.9x0.9x2.5 [mm.sup.3], reconstructed voxel size 0.83x0.83x2.50 [mm.sup.3], total acquisition time 60 s) was performed before administration of the contrast agent, followed by repeat performance of this same sequence at 0, 1, 2, 3, 4, 5, and 7 min after administration of contrast agent of 0.1 mmol/kg gadolinium diethylenetriamine pentaacetic acid (Gd-DTPA).
The image hallmark of SFT on MRI includes a hypointensity T2 mass and strong enhancement of the mass after gadolinium diethylenetriamine pentaacetic acid administration, without enhancement of the adjacent meninges.[sup][3] SFT might display hypointensity signal as compared with the muscle on the unenhanced computed tomography images while it is heterogeneously enhanced on the enhanced images.
The formulas were developed from studies that compared cystatin C concentrations with measured GFRs by using such exogenous markers as iohexol, diethylenetriamine pentaacetic acid or 51Cr-EDTA clearance (4).
We used a basic assay buffer (BSA buffer) consisting of 50 mmol/L Tris-HCI (pH 7.4), 150 mmol/L NaCl, 20 mmol/L diethylenetriamine pentaacetic acid, 5 mg/L tartrazine (Aldrich), 1 g/L Germall II, 10 mg/L Triton X-100, and 5 g/L BSA.
The europium(III) chelate of [N.sup.1]-(4-isothiocyanatobenzyl)diethylenetriamine- [N.sup.1],[N.sup.2],[N.sup.3],[N.sup.4]-tetrakis(acetic acid) [Eu(III)-N1-ITC], DELFIA enhancement solution, DELFIA enhancer, free-PSA calibrators, monoclonal antibody (Mab) H117-coated anti-PSA microtitration wells, streptavidin-coated wells, assay buffer [50 mmol/L Tris-HCl (pH 7.8), 9 g/L NaCl, 0.5 g/L Na[N.sub.3,] 5 g/L bovine serum albumin, 0.1 g/L Tween 40, 0.5 g/L bovine [gamma]-globulin, 20 [micro]mol/L diethylenetriamine pentaacetic acid, 20 mg/L Cherry Red] and wash solution [5 mmol/L Tris-HCl (pH 7.8), 9 g/L NaCl, 0.05 g/L Tween 20] were from Perkin-Elmer Life Sciences (Wallac Oy).
[4] Nonstandard abbreviations: GFR, glomerular filtration rate; DTPA, diethylenetriamine pentaacetic acid; DGF, delayed graft function; and UFC, ultrafiltration coefficient.