phosphodiesterases

(redirected from diesterase)
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phos·pho·di·es·ter·as·es

(fos'fō-dī-es'tĕr-ās'ĕz),
Enzymes cleaving bonds in phosphodiesters, such as those in cAMP or between nucleotides in nucleic acids, liberating smaller polynucleotide or oligonucleotide units or mononucleotides but not orthophosphate.

phos·pho·di·es·ter·as·es

(fos'fō-dī-es'tĕr-ās-ĕz)
Enzymes cleaving phosphodiester bonds, such as those in cyclic adenosine monophosphate or between nucleotides in nucleic acids, liberating smaller poly- or oligonucleotide units or mononucleotides but not inorganic phosphate.
References in periodicals archive ?
Cellular and mitochondrial free radical concentration: The diesterase bond of DCFDA is cleaved in living cells to produce dichlorofluorescin (DCF) which is oxidized by cellular free radicals (14,21,24).
AI172064 56646 Lgals1 Lectin, galactose 3' binding, soluble 1 J02810 24423 Gstm1 Glutathione S-transferase, mu 1 X04229 H32189 565355 50672 Ednrb Endothelin receptor type B X57764 AA818970 U09540 25426 Cyplbl Cytochrome P450 1b1 X83867 AI176856 M14972 50549 Cyp4a10 Cytochrome P450, 4a10 AA924267 D83538 64161 Pik4ca Phosphatidylinositol 4-kinase U39572 J04563 24626 Pde4b Phosphodiesterase 48, cAMP-specific [dunce (Drosophila)- homolog phospho- diesterase E4] M25350 X81395 29225 Cesl Carboxylesterase 1 U10697 (a) http:/www.
showed that PTX can also increase sperm motility by inhibiting the activity of phos-phodiasterase diesterase enzyme to increase the intracellular concentration of cAMP, glycolysis and production of energy (34).
Quercetin reduces basophil degranulation, (109), (110) and histamine release, (111-113) and dampens the inflammatory response directly by modulating certain key enzymes including lipoxygenase, phospholipases, and nucleotide diesterases.