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a nonsteroidal anti-inflammatory drug used systemically as the potassium or sodium salt in the treatment of rheumatic and nonrheumatic inflammatory conditions, and as the potassium salt to relieve pain and dysmenorrhea; also applied topically to the conjunctiva as the sodium salt to reduce ocular inflammation or photophobia after certain kinds of surgery and to the skin to treat actinic keratoses.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


A nonsteroidal anti-inflammatory drug, C14H11Cl2 NO2, used in the form of its potassium salt to treat pain.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.


A non-steroidal anti-inflammatory drug (NSAID) used in the treatment of RHEUMATOID ARTHRITIS and other painful conditions. Brand names are Dicloflex, Diclomax, Motifene, Volraman, Volsaid Retard and Voltarol.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

antiinflammatory drug 

A drug which inhibits or suppresses most inflammatory responses of an allergic, bacterial, traumatic or anaphylactic origin, as well as being immunosuppressant. They include the corticosteroids (e.g. betamethasone, dexamethasone, fluorometholone, hydrocortisone acetate, loteprednol etabonate, prednisolone, rimexolone, triamcinolone). They are sometimes combined with an antibiotic drug (e.g. betamethasone combined with neomycin or sulfacetamide, dexamethasone combined with neomycin or polymyxin B). Corticosteroids have side effects, such as enhancing the activity of herpes simplex virus, fungal overgrowth, raising intraocular pressure or cataract formation.There are other antiinflammatory drugs that are non-steroidal (NSAID) and have little toxicity. They act mainly by blocking prostaglandin synthesis. These include diclofenac sodium, flurbiprofen sodium, indomethacin, ketorolac, nepafenac and oxyphenbutazone. See immunosuppressants; steroid.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann

Patient discussion about diclofenac

Q. HELP...has anyone taken Diclofenac? And did you have any side affects? My boyfriend has started this medication and it is messing with his stomach which we know is a side affect BUT we are wondering if it will get better as his body adjust to it or will it always be this way. THANKS FOR ANY HELP! He is taking for inflamation and back pain.

A. Dear brwnis65, I have been on Diclofenac Sodium 75mg EC 2 a day, for about 2 years now. I have a bad back and arthuritis. What works for me is taking it at night AFTER my evening meal. I also take Prilosec in the morning to help with my reflux problem. I have had no problems with the Diclofenac and my stomach. Make sure you drink a full glass of water when you swallow your pill. Good Luck. egglady1955

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References in periodicals archive ?
Briefly, the diclofenac sodium, sustaining material(s), diluents and buffer were weighed, mixed thoroughly for 10 minutes.
Major Finding: Among older patients treated topically for knee osteoarthritis for 12 weeks, adverse events occurred in 56% using diclofenac sodium 1% gel and in 44% using placebo, with one serious adverse event in the drug group possibly related to treatment.
Like all NSAIDs, diclofenac sodium (Voltaren) gel carries a boxed warning.
Analgesic efficacy of transcutaneous electrical nerve stimulation compared with diclofenac sodium in osteoarthritis of the knee.
In the Disease Activity Score (DAS)28 assessment, which includes analysis of joint swelling and pain, BCM-95 curcumin had the highest impact for reducing disease symptoms, followed by BCM-95 curcumin with diclofenac sodium, with the diclofenac sodium-alone group third.
In conjunction with the approval, the company will manufacture diclofenac sodium topical gel 1% in its plant in Israel.
Diclofenac sodium topical gel is used for the relief of the pain of osteoarthritis of joints, such as the knees and those of the hands.
They were given aspirin (150mg) once a day and diclofenac sodium 50mg three times a day for six consecutive days while use of any other drug was prohibited.
Diclofenac sodium is commonly used for relieving pain and reducing inflammation.
Diclofenac sodium (20 mg/kg), a standard drug also showed similar effects (P < 0.01 vs.
We used diclofenac sodium, octreotid, and their combination for treatment of caerulein-induced experimental acute pancreatitis in mice and evaluated the effects of these treatments on other organ damage.