dichloralphenazone


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dichloralphenazone

 [di-klor″al-fen´ah-zōn]
a complex of chloral hydrate and antipyrine (phenazone), a sedative and hypnotic used in combination with other agents for migraine and tension headache.

dichloralphenazone

A hypnotic drug used for short periods for the management of insomnia and sometimes to control DELIRIUM. A brand name is Welldorm.
References in periodicals archive ?
The third product, acetaminophen, dichloralphenazone, and isometheptene (Epidrin, LarkaDrin, Migragesic IDA) is an over-the-counter tablet.
At the time of evaluation with the headache clinic, she was on topiramate, magnesium, combination of isometheptene mucate, dichloralphenazone, and acetaminophen and as needed oxycodone, which she used 2-3 tablets per week.
A multicenter, double-blind, randomized parallel group study (8) showed no difference between the combination product isometheptene mucate, dichloralphenazone with acetaminophen (Midrin, Duradrin, etc) (used as recommended in the package insert with a maximum of up to 5 tablets within 24 hours) vs oral sumatriptan (initial dose of 25 mg with a repeat 25 mg dose in 2 hours).
Comparative study of a combination of isometheptene mucate, dichloralphenazone with acetaminophen and sumatriptan succinate in the treatment of migraine.
Many other drugs have been used in treating migraines, including: acetaminophen (alone, or in combination with caffeine and butalbital, aspirin and caffeine, or isometheptene and dichloralphenazone); NSAIDs, including aspirin; chlorpromazine (Thorazine); dimenhydrinate (Dramamine); diphenhydramine (Benadryl); morphine; meperidine; intranasal butorphanol (Stadol); and corticosteroids.
Numerous other drugs have been used in treating migraines, including acetaminophen (alone, or in combination with caffeine and butalbital, aspirin and caffeine, or isometheptene and dichloralphenazone); NSAIDs, including aspirin; chlorpromazine (Thorazine); dimenhydrinate (Dramamine); diphenhydramine (Benadryl); morphine; and meperidine.
Other migraine drugs include acetaminophen (alone, or in combination with caffeine and butalbital, aspirin and caffeine, or isometheptene and dichloralphenazone): NSAIDs, including aspirin; chlorpromazine (Thorazine); dimenhydrinate (Dramamine); diphenhydramine (Benadryl); morphine; meperidine; intranasal butorphanol (Stadol); and corticosteroids.
Treatment of migraine with isometheptene, acetaminophen, and dichloralphenazone combination: a double-blind, crossover trial.
Midrin--a capsule headache formulation that combines an analgesic, acetaminophen; a sedative, dichloralphenazone; and a vascular constrictor, isometheptene mucate--was as effective as oral sumatriptan for re-solving migraine headaches in a study with 126 patients, reported Dr.
Medications that patients normally took for a migraine episode included Tylenol (acetaminophen, 29.2% of patients), Demerol (meperidine, 24.7% of patients), Fiorinal (butalbital, aspirin, caffeine; 23.6% of patients), Midrin (isometheptene, dichloralphenazone, acetaminophen; 23.5% of patients), Tylenol with codeine (22.8% of patients), and aspirin (22.1% of patients).